DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14305 and TSSK1B

DIOPT Version :9

Sequence 1:	NP_650732.1	Gene:	CG14305 / 42233	FlyBaseID:	FBgn0038630	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_114417.1	Gene:	TSSK1B / 83942	HGNCID:	14968	Length:	367	Species:	Homo sapiens

Alignment Length:	276	Identity:	128/276 - (46%)
Similarity:	184/276 - (66%)	Gaps:	7/276 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DVDALAQRGYNVGHKIGEGSYATVITAGYADDHGHGVHLACKIIDKAKAPTDFVNKFFPRELEIL 83
            |...|.:|||.:|..:||||||.|.:| |::.....|  |.||||:.|||.||:.||.|||:|||
Human     3 DAAVLKRRGYLLGINLGEGSYAKVKSA-YSERLKFNV--AIKIIDRKKAPADFLEKFLPREIEIL 64

  Fly    84 TKIDHSNIIQIHSILQRG-PKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMSKALKYLHN 147
            ..::|.:||:.:.|.:.. .|::|.|..|..||||..||..|.:.|.:::..|.|:|.|:||.|:
Human    65 AMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHD 129

  Fly   148 LDIAHRDLKCENILLSKRLNIKLADFGFARYC-RDDNGREMKSETYCGSAAYAAPEVVCGRPYDP 211
            ||:.||||||:|:||.|..||||:||.|::.| |||:||...|:|:|||.|||||||:.|.||.|
Human   130 LDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQP 194

  Fly   212 KLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKATVSVLLEPEA 276
            |:.|.|||||||:||:...||:||||:.|:|..|:..:..|.|  .:.::.:.|..:..:|:|:.
Human   195 KVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPR--SKHLTGECKDLIYHMLQPDV 257

  Fly   277 HARWNLREILNCAWLR 292
            :.|.::.|||:..|::
Human   258 NRRLHIDEILSHCWMQ 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14305	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	124/265 (47%)
CG14305	NP_650732.1	S_TKc	28..287	CDD:214567	122/260 (47%)
TSSK1B	NP_114417.1	STKc_TSSK1_2-like	10..272	CDD:271067	125/266 (47%)
TSSK1B	NP_114417.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BHY0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56448
Inparanoid	1	1.050	243	1.000	Inparanoid score	I3315
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D403296at33208
OrthoFinder	1	1.000	-	-		FOG0007569
OrthoInspector	1	1.000	-	-		otm42266
orthoMCL	1	0.900	-	-		OOG6_103794
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5387
SonicParanoid	1	1.000	-	-		X507
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.900