Protein Alignment Tssk and Prkaa2

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_076481.2
• Gene: Prkaa2 / 78975
• RGDID: 620893
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 267
• Identity: 87/267 - (32%)
• Similarity: 140/267 - (52%)
• Gaps: 15/267 - (5%)

  Fly    28 YNVGHKIGEGSYATVITAGYADDHGHGVHLACKIIDKAKAPT-DFVNKFFPRELEILTKIDHSNI 91
            |.:|..:|.|::..| ..|.....||.|  |.||:::.|..: |.|.| ..||::.|....|.:|
  Rat    16 YVLGDTLGVGTFGKV-KIGEHQLTGHKV--AVKILNRQKIRSLDVVGK-IKREIQNLKLFRHPHI 76

  Fly    92 IQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLK 156
            |:::.::......|:.|.|...|:|..:|.:.|.::|.:::..|.|:..|:.|.|...:.|||||
  Rat    77 IKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDLK 141

  Fly   157 CENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLGV 221
            .||:||..::|.|:||||.:....|  |..::  |.|||..||||||:.||.|.....|.||.||
  Rat   142 PENVLLDAQMNAKIADFGLSNMMSD--GEFLR--TSCGSPNYAAPEVISGRLYAGPEVDIWSCGV 202

  Fly   222 ILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKATVSV-LLEPEAHARWNLREI 285
            ||:.::...:||||.::..|.:..|...|.....|..:|     ||:.: :|:.:...|..:::|
  Rat   203 ILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSI-----ATLLMHMLQVDPLKRATIKDI 262

  Fly   286 LNCAWLR 292
            ....|.:
  Rat   263 REHEWFK 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	86/264 (33%)
Prkaa2	NP_076481.2	STKc_AMPK_alpha	13..268	CDD:270981	86/264 (33%)
		UBA_AID_AAPK2	285..349	CDD:270587
		AIS. /evidence=ECO:0000250|UniProtKB:Q13131	291..376
		AMPKA2_C	395..550	CDD:213385
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	478..520