Protein Alignment Tssk and Tssk5

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_898922.2
• Gene: Tssk5 / 73542
• MGIID: 1920792
• Length: 372
• Species: Mus musculus
• Alignment Length: 318
• Identity: 103/318 - (32%)
• Similarity: 157/318 - (49%)
• Gaps: 44/318 - (13%)

  Fly    10 IRQLGTRSSD-------VDALAQRGYNV-GHKIGEGSYATVITAGYA--DDHGHGVHL------- 57
            :|....|.||       |......||.: ..|||.|:::.|..| ||  :...|...|
Mouse     1 MRSSSWRKSDQRVFIEQVRECMNNGYLLSSKKIGSGAFSKVYLA-YATRERMKHNPRLSSDLRGK 64

  Fly    58 -----ACKIIDKAKAPTDFVNKFFPRE-LEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDL 116
                 |.||:..|:||.::..||.||| |.:.....|.||:|::...|...:.::.:..|..|||
Mouse    65 RHTMVAIKIVSMAEAPAEYSRKFLPREILSLNATYKHMNIVQLYETYQNSQRSYLVLELAARGDL 129

  Fly   117 LSHIK-----RSGP-IDEKQSKIWFFQMSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGF 175
            |.||.     |..| ::|::::..|:|:..|:.:.||:.|.|||||||||||..:..|||.||||
Mouse   130 LEHINAVSDLRCCPGLEEEEARRLFWQLVSAVAHCHNVGIVHRDLKCENILLDDQGFIKLTDFGF 194

  Fly   176 ARYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTK 240
            |.:....|.   ...|:|||.||.|||::..:.|:.:.||.||||:||..|::.|:||.
Mouse   195 ANWVGLKNS---LLSTFCGSVAYTAPEILMSKKYNGEQADLWSLGIILHAMVSGKLPFK------ 250

  Fly   241 LLEDQRNRKFAFRRK---LQETISAQAKATVSVLLEPEAHARWNLREILNCAWLRTVE 295
              |.|.:|.....|:   .:..:|.:.:..:..||:.....|.:|:::....|:...|
Mouse   251 --EHQPHRMLNLIRRGPIFRPGLSPECRDLIRGLLQLHPCERLDLQQVAAHCWMLPAE 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	96/288 (33%)
Tssk5	NP_898922.2	Protein Kinases, catalytic domain	26..301	CDD:473864	95/286 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..372