Protein Alignment Tssk and Sik3

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_081774.3
• Gene: Sik3 / 70661
• MGIID: 2446296
• Length: 1369
• Species: Mus musculus
• Alignment Length: 285
• Identity: 92/285 - (32%)
• Similarity: 154/285 - (54%)
• Gaps: 32/285 - (11%)

  Fly    22 ALAQRG--------YNVGHKIGEGSYATVITAGYADDHGHGVHL------ACKIIDKAKAPTDFV 72
            |.|.||        |.:...||:|::|.|..|         .||      |.|||||::...:.:
Mouse    52 APASRGSMAARIGYYEIDRTIGKGNFAVVKRA---------THLVTKAKVAIKIIDKSQLDEENL 107

  Fly    73 NKFFPRELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQ 137
            .|.| ||::|:..:.|.:||:::.:::....|::...||..|::..|:...|.:.||:::..|.|
Mouse   108 KKIF-REVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQ 171

  Fly   138 MSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPE 202
            :..|:.:.|..:|.|||||.||:||...||||:|||||:.....  |:.:|  |:|||..|||||
Mouse   172 IVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTP--GQLLK--TWCGSPPYAAPE 232

  Fly   203 VVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKAT 267
            :..|:.||....|.|||||:|::::...:|||.|.|..|    |.|..:.:.::...:|.:.:..
Mouse   233 LFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNL----RARVLSGKFRIPFFMSTECEHL 293

  Fly   268 VSVLLEPEAHARWNLREILNCAWLR 292
            :..:|..:.:.|.::.:|....|::
Mouse   294 IRHMLVLDPNKRLSMEQICRHKWMK 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	88/277 (32%)
Sik3	NP_081774.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..55		1/2 (50%)
		STKc_SIK	65..317	CDD:270973	87/269 (32%)
		UBA_SIK3	346..390	CDD:270593
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	775..821
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	942..993
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1314..1338