Protein Alignment Tssk and mark2

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: XP_012808991.1
• Gene: mark2 / 594939
• XenbaseID: XB-GENE-876451
• Length: 792
• Species: Xenopus tropicalis
• Alignment Length: 281
• Identity: 92/281 - (32%)
• Similarity: 148/281 - (52%)
• Gaps: 18/281 - (6%)

  Fly    28 YNVGHKIGEGSYATVITAGYADDHGHGVHLACKIIDKAKAPTDFVNKFFPRELEILTKIDHSNII 92
            |.:...||:|::|.|..|.:...   |..:|.|||||.:..:..:.|.| ||:.|:..::|.||:
 Frog    64 YRLLKTIGKGNFAKVKLARHVLT---GKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIV 124

  Fly    93 QIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLKC 157
            ::..:::....:::.|.||..|::..::...|.:.||:::..|.|:..|::|.|...|.|||||.
 Frog   125 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKLIVHRDLKA 189

  Fly   158 ENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLGVI 222
            ||:||...:|||:|||||:......|    |.:|:|||..|||||:..|:.||....|.||||||
 Frog   190 ENLLLDSDMNIKIADFGFSNEFTFGN----KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 250

  Fly   223 LFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKATVSVLLEPEAHARWNLREILN 287
            |:.:::..:|||..||.:|    |.|....:.::...:|...:..:...|......|..|.:|:.
 Frog   251 LYTLVSGSLPFDGQNLKEL----RERVLRGKYRIPFYMSTDCENLLKKFLILNPAKRGTLEQIMR 311

  Fly   288 CAWLRTVEESQ------TPIP 302
            ..|:....|..      .|||
 Frog   312 DRWMNVGHEEDELKPYVEPIP 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	87/262 (33%)
mark2	XP_012808991.1	STKc_MARK	63..315	CDD:270974	87/262 (33%)
		UBA_MARK2	333..374	CDD:270589	92/281 (33%)
		MARK2_C	693..791	CDD:213386