DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14305 and CG10177

DIOPT Version :9

Sequence 1:	NP_650732.1	Gene:	CG14305 / 42233	FlyBaseID:	FBgn0038630	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster

Alignment Length:	237	Identity:	62/237 - (26%)
Similarity:	118/237 - (49%)	Gaps:	22/237 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 KIIDKAKAPTDFVNKFFPRELEILTKI-DHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRS 123
            |:::|.....|..:.:.  |.|:|.:: .|.|||::...::....::..:.:.: .::...|::.
  Fly   178 KMVNKQTQSNDRGDTYM--EAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLD-CNMQKVIQKR 239

  Fly   124 GPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLKCENILL---SKRLN---IKLADFGFARYCRDD 182
            |.:.|..::........||.::|.|.:.|||:|.||:|:   |.:.|   :|:|:|..|.|.|.
  Fly   240 GILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRG- 303

  Fly   183 NGREMKSETY--CGSAAYAAPEVVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDS--NLTKLLE 243
                  |:.|  ||:..|.|||::....||.:: |:|||||.||.|:..||||..:  |..::..
  Fly   304 ------SKLYVRCGTPCYMAPEMIAMSGYDYQV-DSWSLGVTLFYMLCGKMPFASACKNSKEIYA 361

  Fly   244 DQRNRKFAFRRKLQETISAQAKATVSVLLEPEAHARWNLREI 285
            ...:....:.:.::..:|.:|...:..||..:...|..:.|:
  Fly   362 AIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAEL 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14305	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	62/237 (26%)
CG14305	NP_650732.1	S_TKc	28..287	CDD:214567	62/237 (26%)
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	62/237 (26%)
		PKc_like	164..403	CDD:304357	61/235 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461597
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930