Protein Alignment Tssk and Sik3

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_611361.4
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Alignment Length: 284
• Identity: 93/284 - (32%)
• Similarity: 154/284 - (54%)
• Gaps: 25/284 - (8%)

  Fly    15 TRSSDVDALAQRG-YNVGHKIGEGSYATV------ITAGYADDHGHGVHLACKIIDKAKAPTDFV 72
            |....||.|.:.| |.:...||:|::|.|      :|.         ..:|.|||||.....:::
  Fly    27 TSKISVDKLLRVGYYELEKTIGKGNFAVVKLATNIVTK---------TKVAIKIIDKTCLNEEYL 82

  Fly    73 NKFFPRELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQ 137
            ||.| ||:.||..:.|.:|.:::.:::....|::...||.||::..|:..:|.:.|.::...|.|
  Fly    83 NKTF-REIAILKSLRHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQ 146

  Fly   138 MSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPE 202
            :..|:.|.|...:.|||||.||:||.|.:|||||||||:.:.  :.|..:|  |:|||..|||||
  Fly   147 LVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGFSNHY--EEGATLK--TWCGSPPYAAPE 207

  Fly   203 VVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKAT 267
            |..|..||...:|.|||||:|:.::...:|||...:.:|    ::|....:.::...:|.:.:..
  Fly   208 VFQGLEYDGPKSDIWSLGVVLYALVCGALPFDGKTILEL----KSRVVLGKFRIPFFMSQECEQL 268

  Fly   268 VSVLLEPEAHARWNLREILNCAWL 291
            :..:|..|...|:.:::|:...||
  Fly   269 IRNMLVVEPDRRYTIKQIIKHRWL 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	87/270 (32%)
Sik3	NP_611361.4	Protein Kinases, catalytic domain	40..292	CDD:473864	86/269 (32%)
		UBA_SIK	335..380	CDD:270523