Protein Alignment Tssk and melk

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_996771.2
• Gene: melk / 30724
• ZFINID: ZDB-GENE-990603-5
• Length: 676
• Species: Danio rerio
• Alignment Length: 293
• Identity: 84/293 - (28%)
• Similarity: 149/293 - (50%)
• Gaps: 33/293 - (11%)

  Fly    20 VDALAQ--RGYNVGHKIGEGSYATV------ITAGYADDHGHGVHLACKIIDKAKAPTDFVNKFF 76
            ||:.::  |.|.|...||.|.:|.|      :|         |..:|.||::|.....|     .
Zfish     3 VDSTSELLRHYEVYETIGSGGFAKVKLGRHKLT---------GEKVAIKIMEKKDLGDD-----L 53

  Fly    77 PR---ELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQM 138
            ||   |:|.:..:.|.::.:::.:::...||::.:.|...|:|..:|.....:.|::::::|.|:
Zfish    54 PRVKIEIEAMKNLSHQHVCRLYHVIETTSKIYMVLEYCPGGELFDYIIAKDRLSEEETRVFFRQI 118

  Fly   139 SKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEV 203
            ..||.|:|:...||||||.||:|:.:..|:||.|||.....:...|.|:.  |.|||.||||||:
Zfish   119 ISALAYVHSQGYAHRDLKPENLLIDEDHNLKLIDFGLCAKPKGGLGFELL--TCCGSPAYAAPEL 181

  Fly   204 VCGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKATV 268
            :.|:.|....||.||:||:|:.::...:||||.|...|.......|::    ....:|..:...:
Zfish   182 IQGKAYIGSEADVWSMGVLLYALLCGFLPFDDDNCMVLYRKITRGKYS----NPHWLSPSSILLL 242

  Fly   269 SVLLEPEAHARWNLREILNCAWLRTVEESQTPI 301
            :.:::.:...|..::.:|:..|  .:....||:
Zfish   243 NQMMQVDPKRRLTVKHLLDHPW--AMRGYSTPV 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	78/272 (29%)
melk	NP_996771.2	STKc_MELK	9..264	CDD:270980	79/274 (29%)
		UBA_MELK	283..334	CDD:270526
		UBA-like. /evidence=ECO:0000250	284..323
		Autoinhibitory region. /evidence=ECO:0000250	328..673
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..518
		MELK_C	577..671	CDD:213383