DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14305 and kin1

DIOPT Version :9

Sequence 1:	NP_650732.1	Gene:	CG14305 / 42233	FlyBaseID:	FBgn0038630	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_596106.1	Gene:	kin1 / 2540792	PomBaseID:	SPBC4F6.06	Length:	891	Species:	Schizosaccharomyces pombe

Alignment Length:	289	Identity:	88/289 - (30%)
Similarity:	136/289 - (47%)	Gaps:	43/289 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 YNVGHKIGEGSYATVITAGYADDHGHGVHLACKI-------IDKAKAPTDF---------VNKFF 76
            |.:|..||.||...|..|.:...   |...|.||       |.||||....         .||..
pombe   125 YVLGKTIGAGSMGKVKVAHHLKT---GEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNKEI 186

  Fly    77 --PRELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMS 139
              .||..:.|.:.|..|.:...:.......::...:.:.|.:|.:|...|.:.|||::.:..|:.
pombe   187 RTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQIG 251

  Fly   140 KALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEVV 204
            .||.|||...:.|||||.||||:||..:||:.|||.:...|    |:.:..|:|||..:||||::
pombe   252 SALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLYR----RQSRLRTFCGSLYFAAPELL 312

  Fly   205 CGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQE-------TISA 262
            ..:||.....|.||.|::|::::..|:||||.|::           |...|:::       .:|:
pombe   313 NAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMS-----------ALHAKIKKGTVEYPSYLSS 366

  Fly   263 QAKATVSVLLEPEAHARWNLREILNCAWL 291
            ..|..:|.:|..:...|..|.|:||..|:
pombe   367 DCKGLLSRMLVTDPLKRATLEEVLNHPWM 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14305	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	87/287 (30%)
CG14305	NP_650732.1	S_TKc	28..287	CDD:214567	85/283 (30%)
kin1	NP_596106.1	STKc_Kin1_2	123..395	CDD:270979	87/287 (30%)
		S_TKc	125..395	CDD:214567	87/287 (30%)
		MARK_C_like	753..889	CDD:213377
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000