Protein Alignment Tssk and aak-2

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_510710.2
• Gene: aak-2 / 181727
• WormBaseID: WBGene00020142
• Length: 626
• Species: Caenorhabditis elegans
• Alignment Length: 322
• Identity: 92/322 - (28%)
• Similarity: 156/322 - (48%)
• Gaps: 46/322 - (14%)

  Fly     2 SKYNSSAGIRQLGTRSSDVDALAQRGYNVGHKI-----GEGSYATVITAGYADDHGHGVH----- 56
            ||.:|..|  :..|:... :..||  ..:||.|     |.|::..|..         |:|
 Worm    61 SKMSSPGG--ETSTKQQQ-ELKAQ--IKIGHYILKETLGVGTFGKVKV---------GIHETTQY 111

  Fly    57 -LACKIIDKAKAPT-DFVNKFFPRELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSH 119
             :|.||:::.|..: |.|.| ..||::.|:...|.:||:::.::.....||:.|.:...|:|..:
 Worm   112 KVAVKILNRQKIKSLDVVGK-IRREIQNLSLFRHPHIIRLYQVISTPSDIFMIMEHVSGGELFDY 175

  Fly   120 IKRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNG 184
            |.:.|.:...:::.:|.|:...:.|.|...:.|||||.||:||.::.|:|:||||.:....|  |
 Worm   176 IVKHGRLKTAEARRFFQQIISGVDYCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTD--G 238

  Fly   185 REMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRK 249
            ..::  |.|||..||||||:.|:.|.....|.||.||||:.::...:||||.::..|....::..
 Worm   239 DFLR--TSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGV 301

  Fly   250 FAFRRKLQETI----------SAQAKATVSVLLEPEAHARWNLREILNCAWLRTVEESQTPI 301
            |.....|:..|          ....:||:..::   || .|..:::.|..: ..:.||:..|
 Worm   302 FPTPDFLERPIVNLLHHMLCVDPMKRATIKDVI---AH-EWFQKDLPNYLF-PPINESEASI 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	82/285 (29%)
aak-2	NP_510710.2	STKc_AMPK_alpha	84..339	CDD:270981	80/272 (29%)
		UBA_AID_AMPKalpha	356..419	CDD:270521	1/3 (33%)
		AMPKA_C	462..624	CDD:213378