DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14305 and Y38H8A.4

DIOPT Version :9

Sequence 1:	NP_650732.1	Gene:	CG14305 / 42233	FlyBaseID:	FBgn0038630	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_502595.1	Gene:	Y38H8A.4 / 178314	WormBaseID:	WBGene00012638	Length:	331	Species:	Caenorhabditis elegans

Alignment Length:	269	Identity:	99/269 - (36%)
Similarity:	145/269 - (53%)	Gaps:	17/269 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 HK------IGEGSYATVITAGYADDHGHGVHLACKIID--KAKAPTDFVNKFFPRELEILTKIDH 88
            ||      :|.|||:.|..|.:.|..   :.:|.|:|:  ..:...|::.||.|||.||:..:.|
Worm    34 HKLKFDKILGSGSYSRVARATWGDKK---LEVAAKVINITPTREKDDYIKKFLPREKEIVKLLKH 95

  Fly    89 SNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHR 153
            .|:.:::.::.....|.....:...||||..:|:...:.|:.:|..|.|...||.:|.:.:|.||
Worm    96 DNVCRLYEMISFPDHIIFVTEFCAGGDLLRKMKKIKTMSEENAKFTFRQFIAALMHLQSYNIVHR 160

  Fly   154 DLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWS 218
            |||||||.|.|..|:||.||||:|..:...    ||.|:|||.||.|||::.||.|.....|.||
Worm   161 DLKCENIFLDKYENVKLGDFGFSRILKPGE----KSGTFCGSRAYVAPEILRGREYSGNAVDVWS 221

  Fly   219 LGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKATVSVLLEPEAHARWNLR 283
            .||||:||:...|||||.:.|:::|.|...|..|.:..  |.|..:||.:..:|:|.|..|...:
Worm   222 TGVILYIMLVGTMPFDDRDPTRMIERQLAHKIKFGKTC--TASIHSKALILEILQPHAPNRPTYK 284

  Fly   284 EILNCAWLR 292
            .|....||:
Worm   285 AICESEWLK 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14305	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	97/266 (36%)
CG14305	NP_650732.1	S_TKc	28..287	CDD:214567	97/262 (37%)
Y38H8A.4	NP_502595.1	PKc_like	38..292	CDD:389743	95/262 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163984
Domainoid	1	1.000	180	1.000	Domainoid score	I2088
eggNOG	1	0.900	-	-		E33208_3BHY0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H56448
Inparanoid	1	1.050	181	1.000	Inparanoid score	I2647
Isobase	1	0.950	-	0	Normalized mean entropy	S1732
OMA	1	1.010	-	-		QHG29081
OrthoDB	1	1.010	-	-		D403296at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4795
orthoMCL	1	0.900	-	-		OOG6_103794
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X507
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.720