Protein Alignment Tssk and Mark3

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: XP_006515574.1
• Gene: Mark3 / 17169
• MGIID: 1341865
• Length: 806
• Species: Mus musculus
• Alignment Length: 290
• Identity: 93/290 - (32%)
• Similarity: 153/290 - (52%)
• Gaps: 13/290 - (4%)

  Fly     8 AGIRQLGTRSSDVDALAQRG-YNVGHKIGEGSYATVITAGYADDHGHGVHLACKIIDKAKAPTDF 71
            :|.|...:.:|..|.....| |.:...||:|::|.|..|.:...   |..:|.|||||.:.....
Mouse    35 SGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILT---GREVAIKIIDKTQLNPTS 96

  Fly    72 VNKFFPRELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFF 136
            :.|.| ||:.|:..::|.||:::..:::....:::.|.||..|::..::...|.:.||:::..|.
Mouse    97 LQKLF-REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFR 160

  Fly   137 QMSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAP 201
            |:..|::|.|...|.|||||.||:||...:|||:|||||:    ::.....|.:|:|||..||||
Mouse   161 QIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFS----NEFTVGSKLDTFCGSPPYAAP 221

  Fly   202 EVVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKA 266
            |:..|:.||....|.|||||||:.:::..:|||..||.:|    |.|....:.::...:|...:.
Mouse   222 ELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL----RERVLRGKYRIPFYMSTDCEN 282

  Fly   267 TVSVLLEPEAHARWNLREILNCAWLRTVEE 296
            .:...|......|..|.:|:...|:....|
Mouse   283 LLKRFLVLNPVKRGTLEQIMKDRWINAGHE 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	87/264 (33%)
Mark3	XP_006515574.1	STKc_MARK	55..307	CDD:270974	86/263 (33%)
		UBA_MARK3_4	325..367	CDD:270590
		MARK1-3_C	707..804	CDD:213381