Protein Alignment Tssk and Mark2

DIOPT Version :10

• Sequence 1: NP_650732.1
• Gene: Tssk / 42233
• FlyBaseID: FBgn0038630
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: XP_006526704.1
• Gene: Mark2 / 13728
• MGIID: 99638
• Length: 851
• Species: Mus musculus
• Alignment Length: 308
• Identity: 96/308 - (31%)
• Similarity: 159/308 - (51%)
• Gaps: 19/308 - (6%)

  Fly     2 SKYNSSAGIRQLGTRSSDVDALAQRG-YNVGHKIGEGSYATVITAGYADDHGHGVHLACKIIDKA 65
            ||.:|.:.:.:....::..|.....| |.:...||:|::|.|..|.:...   |..:|.|||||.
Mouse    36 SKPSSKSNMLRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILT---GKEVAVKIIDKT 97

  Fly    66 KAPTDFVNKFFPRELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQ 130
            :..:..:.|.| ||:.|:..::|.||:::..:::....:::.|.||..|::..::...|.:.||:
Mouse    98 QLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKE 161

  Fly   131 SKIWFFQMSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGS 195
            ::..|.|:..|::|.|...|.|||||.||:||...:|||:|||||:......|    |.:|:|||
Mouse   162 ARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGN----KLDTFCGS 222

  Fly   196 AAYAAPEVVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETI 260
            ..|||||:..|:.||....|.|||||||:.:::..:|||..||.:|    |.|....:.::...:
Mouse   223 PPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL----RERVLRGKYRIPFYM 283

  Fly   261 SAQAKATVSVLLEPEAHARWNLREILNCAWLRTVEESQ------TPIP 302
            |...:..:...|......|..|.:|:...|:....|..      .|:|
Mouse   284 STDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLP 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tssk	NP_650732.1	STKc_TSSK-like	27..291	CDD:270982	88/264 (33%)
Mark2	XP_006526704.1	STKc_MARK	62..314	CDD:270974	87/263 (33%)
		UBA_MARK2	332..373	CDD:270589	96/308 (31%)
		MARK2_C	752..850	CDD:213386