DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tssk and Mark1

DIOPT Version :10

Sequence 1:NP_650732.1 Gene:Tssk / 42233 FlyBaseID:FBgn0038630 Length:302 Species:Drosophila melanogaster
Sequence 2:XP_038946210.1 Gene:Mark1 / 117016 RGDID:619882 Length:794 Species:Rattus norvegicus


Alignment Length:271 Identity:90/271 - (33%)
Similarity:147/271 - (54%) Gaps:12/271 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 YNVGHKIGEGSYATVITAGYADDHGHGVHLACKIIDKAKAPTDFVNKFFPRELEILTKIDHSNII 92
            |.:...||:|::|.|..|.:...   |..:|.|||||.:.....:.|.| ||:.|:..::|.||:
  Rat    60 YRLQKTIGKGNFAKVKLARHVLT---GREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIV 120

  Fly    93 QIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLKC 157
            ::..:::....:::.|.||..|::..::...|.:.||:::..|.|:..|::|.|...|.|||||.
  Rat   121 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKA 185

  Fly   158 ENILLSKRLNIKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLGVI 222
            ||:||...:|||:|||||:......|    |.:|:|||..|||||:..|:.||....|.||||||
  Rat   186 ENLLLDADMNIKIADFGFSNEFTVGN----KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 246

  Fly   223 LFIMMNAKMPFDDSNLTKLLEDQRNRKFAFRRKLQETISAQAKATVSVLLEPEAHARWNLREILN 287
            |:.:::..:|||..||.:|    |.|....:.::...:|...:..:..||......|.:|.:|:.
  Rat   247 LYTLVSGSLPFDGQNLKEL----RERVLRGKYRVPFYMSTDCENLLKKLLVLNPIKRGSLEQIMK 307

  Fly   288 CAWLRTVEESQ 298
            ..|:....|.:
  Rat   308 DRWMNVGHEEE 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TsskNP_650732.1 STKc_TSSK-like 27..291 CDD:270982 88/262 (34%)
Mark1XP_038946210.1 STKc_MARK 59..311 CDD:270974 88/262 (34%)
UBA_MARK1 331..371 CDD:270588
MARK1-3_C 695..792 CDD:213381
Blue background indicates that the domain is not in the aligned region.

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