DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7694 and Rnf126

DIOPT Version :9

Sequence 1:	NP_001138076.1	Gene:	CG7694 / 42230	FlyBaseID:	FBgn0038627	Length:	147	Species:	Drosophila melanogaster
Sequence 2:	NP_653111.1	Gene:	Rnf126 / 70294	MGIID:	1917544	Length:	313	Species:	Mus musculus

Alignment Length:	112	Identity:	41/112 - (36%)
Similarity:	57/112 - (50%)	Gaps:	7/112 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LGHEPTGPLGANDL-----ARNLKRLQVLAIMNGIDMEIEVPEASKRAILELPVHEIVKSDEGGD 67
            ||..|.|.|.:|.:     |..|..: :..::|..: ....|.|.|..|..||...:.:...|..
Mouse   166 LGLGPWGVLHSNPMDYAWGANGLDTI-ITQLLNQFE-NTGPPPADKEKIQALPTVPVTEEHVGSG 228

  Fly    68 LECSVCKEPAEEGQKYRILPCKHEFHEECILLWLKKTNSCPLCRYEL 114
            |||.||||....|:..|.|||.|.||:.||:.||::.:|||:||..|
Mouse   229 LECPVCKEDYALGESVRQLPCNHLFHDSCIVPWLEQHDSCPVCRKSL 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7694	NP_001138076.1	zf-RING_2	69..111	CDD:290367	21/41 (51%)
Rnf126	NP_653111.1	Required for interaction with BAG6. /evidence=ECO:0000250\|UniProtKB:Q9BV68	5..100
		zinc_ribbon_9	10..40	CDD:373030
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..63
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	95..128
		Sufficient for interaction with AICDA. /evidence=ECO:0000250\|UniProtKB:Q9BV68	202..306		32/74 (43%)
		RING-H2_RNF126	230..273	CDD:319715	22/42 (52%)
		RING-H2 finger (C3H2C3-type)	231..271	CDD:319715	20/39 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	279..313
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249953at2759
OrthoFinder	1	1.000	-	-		FOG0000184
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920