DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7694 and RNF130

DIOPT Version :9

Sequence 1:	NP_001138076.1	Gene:	CG7694 / 42230	FlyBaseID:	FBgn0038627	Length:	147	Species:	Drosophila melanogaster
Sequence 2:	XP_024301897.1	Gene:	RNF130 / 55819	HGNCID:	18280	Length:	448	Species:	Homo sapiens

Alignment Length:	127	Identity:	38/127 - (29%)
Similarity:	59/127 - (46%)	Gaps:	29/127 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 RNLKRLQVLAIMNGIDMEIEVPEASKRAILELPVHEIVKSDEGGDLE---CSVCKEPAEEGQKYR 84
            ||.:||               .:|:|:||.:|....:.|.|:..|.:   |:||.|..::....|
Human   229 RNQRRL---------------GDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVR 278

  Fly    85 ILPCKHEFHEECILLWLKKTNSCPLCRYELE-----------TDDPVYEELRRFRQDEANRR 135
            ||||||.||:.|:..||.:..:||:|:..:.           ||:..::..|..|....|||
Human   279 ILPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRR 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7694	NP_001138076.1	zf-RING_2	69..111	CDD:290367	18/44 (41%)
RNF130	XP_024301897.1	PA_GRAIL_like	40..179	CDD:239037
		zf-rbx1	<197..>306	CDD:331150	31/91 (34%)
		RING_Ubox	262..310	CDD:327409	19/47 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910