DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7694 and RNF126

DIOPT Version :9

Sequence 1:NP_001138076.1 Gene:CG7694 / 42230 FlyBaseID:FBgn0038627 Length:147 Species:Drosophila melanogaster
Sequence 2:NP_919442.1 Gene:RNF126 / 55658 HGNCID:21151 Length:311 Species:Homo sapiens


Alignment Length:90 Identity:35/90 - (38%)
Similarity:47/90 - (52%) Gaps:10/90 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 NGIDMEIE----------VPEASKRAILELPVHEIVKSDEGGDLECSVCKEPAEEGQKYRILPCK 89
            ||:|..|.          .|.|.|..|..||...:.:...|..|||.|||:....|::.|.|||.
Human   184 NGLDAIITQLLNQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYALGERVRQLPCN 248

  Fly    90 HEFHEECILLWLKKTNSCPLCRYEL 114
            |.||:.||:.||::.:|||:||..|
Human   249 HLFHDGCIVPWLEQHDSCPVCRKSL 273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7694NP_001138076.1 zf-RING_2 69..111 CDD:290367 20/41 (49%)
RNF126NP_919442.1 Required for interaction with BAG6. /evidence=ECO:0000269|PubMed:24981174 5..100
zinc_ribbon_9 10..40 CDD:373030
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..64
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 94..132
Sufficient for interaction with AICDA. /evidence=ECO:0000269|PubMed:23277564 200..304 31/74 (42%)
RING-H2_RNF126 228..271 CDD:319715 21/42 (50%)
RING-H2 finger (C3H2C3-type) 229..269 CDD:319715 19/39 (49%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 277..311
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1249953at2759
OrthoFinder 1 1.000 - - FOG0000184
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.920

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