DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7691 and scrt1b

DIOPT Version :9

Sequence 1:	NP_650728.1	Gene:	CG7691 / 42228	FlyBaseID:	FBgn0038626	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001014369.1	Gene:	scrt1b / 541533	ZFINID:	ZDB-GENE-050327-72	Length:	279	Species:	Danio rerio

Alignment Length:	312	Identity:	85/312 - (27%)
Similarity:	125/312 - (40%)	Gaps:	83/312 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRIF----------------------RSFLSDRYNGK-------QERFYDRYEDFCQVIPNLPP 36
            |||.|                      |:.||.|.:.|       ....||...|....:|:  |
Zfish     1 MPRSFLVKKVKLDDFSSSELESAYGRSRTDLSFRIHDKGYISDYITPAIYDGESDGGTKVPS--P 63

  Fly    37 MPRPKTNHHSRVA---TKPE-PKTNVKFTYCFGQSEPSGDWRQGDDIPIVVRREMEERLGIQLMS 97
            .|...:||....|   .:|: |::.:...|..|.:..|    :|..:......:...|..:
Zfish    64 GPIYDSNHSDYGAPDSDQPDSPQSEITSGYINGDNAVS----EGYTVDAFFITDGRSRRKV---- 120

  Fly    98 VLPITES-SLLSHTIWELKMPGESFDSIPKTRNGIKVGIITVTAESKQTR----TKLKRKGPILA 157
               |:.| :|..||..|.   |:::    .|.:.:        :..|||.    :|:.:|.|...
Zfish   121 ---ISGSRTLQRHTCNEC---GKTY----ATSSNL--------SRHKQTHRSLDSKMAKKCPTCG 167

  Fly   158 NVTVPSNIVEIPPIQQRKMPEKRRLKRVGGQFECIDCDKKFDHSWMLTAHTRTHTGEKPFVCPDG 222
            .|     .|.:|.:....:....:.|       |..|.|.|...|:|..|.|:|||||||.|  .
Zfish   168 KV-----YVSMPAMAMHLLTHDLKHK-------CDICGKAFSRPWLLQGHMRSHTGEKPFGC--A 218

  Fly   223 SCRKAFSDRSNLRSHQRTMGHHEWQH-QCGQCGKYFSQFSYLNRHSLDACRK 273
            .|.|||:||||||:|.:|  |..::| :|.:|.|.|...||||:|...||.|
Zfish   219 HCGKAFADRSNLRAHMQT--HSAFKHFKCKRCNKTFVLKSYLNKHYESACFK 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7691	NP_650728.1	COG5048	188..>271	CDD:227381	39/83 (47%)
		C2H2 Zn finger	191..211	CDD:275368	8/19 (42%)
		zf-H2C2_2	203..229	CDD:290200	14/25 (56%)
		C2H2 Zn finger	219..244	CDD:275368	13/24 (54%)
		C2H2 Zn finger	250..266	CDD:275368	8/15 (53%)
scrt1b	NP_001014369.1	zf-C2H2	130..152	CDD:278523	7/36 (19%)
		C2H2 Zn finger	132..152	CDD:275368	5/34 (15%)
		C2H2 Zn finger	163..180	CDD:275371	4/21 (19%)
		COG5048	187..>263	CDD:227381	40/86 (47%)
		zf-C2H2	187..209	CDD:278523	9/28 (32%)
		C2H2 Zn finger	189..209	CDD:275368	8/19 (42%)
		C2H2 Zn finger	217..237	CDD:275368	13/23 (57%)
		zf-C2H2	217..237	CDD:278523	13/23 (57%)
		zf-H2C2_2	229..253	CDD:290200	10/25 (40%)
		C2H2 Zn finger	245..261	CDD:275368	8/15 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810