DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7691 and CG10348

DIOPT Version :9

Sequence 1:	NP_650728.1	Gene:	CG7691 / 42228	FlyBaseID:	FBgn0038626	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	68/282 - (24%)
Similarity:	102/282 - (36%)	Gaps:	88/282 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PNLPPMPRPKTNHHSRVATKPEPKTNVKFTYCFGQSEPSGDWRQGDDIPIV---VRREMEERLGI 93
            ||.||:..|:.:                                   ||.|   :...|.:.|.:
  Fly   182 PNAPPLTPPQCS-----------------------------------IPAVHPTLLEAMTKNLPL 211

  Fly    94 QLMSVL----------PITESSLLSHTIWELKMPGESFDSIPKTRNGIKVGIITVTAESKQTRTK 148
            |..:|.          |...||          ..|..|    ..|:.:|...:|....::|.:.:
  Fly   212 QYRNVFAGVLPGKVNSPAASSS----------PTGADF----PFRHPLKKCELTWPPPTEQLQLE 262

  Fly   149 LKRKGPILANVTVPSNIVEIPPIQ--QRKMPEKRRLKRVGG------------QFECIDCDKKFD 199
            |....|.|      |.::..|.:|  |.:...|.|....||            ::.|..|.|.|.
  Fly   263 LPHPNPKL------SPVLPHPQLQDYQTRRKNKARTAATGGNATPNLPQRNKDRYTCKFCGKVFP 321

  Fly   200 HSWMLTAHTRTHTGEKPFVCPDGSCRKAFSDRSNLRSHQRTMGHHEWQHQCGQCGKYFSQFS--- 261
            .|..||.|.||||||:|:.|.  .|.::||..|||:.|.|.:.:.|...:|..|.:.|.|.:
  Fly   322 RSANLTRHLRTHTGEQPYKCK--YCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLD 384

  Fly   262 -YLNRHSLDACRKYLLSVMHKR 282
             :|.:|..||.....||.:.:|
  Fly   385 RHLKKHESDAVSLSALSGVSER 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7691	NP_650728.1	COG5048	188..>271	CDD:227381	32/86 (37%)
		C2H2 Zn finger	191..211	CDD:275368	9/19 (47%)
		zf-H2C2_2	203..229	CDD:290200	12/25 (48%)
		C2H2 Zn finger	219..244	CDD:275368	9/24 (38%)
		C2H2 Zn finger	250..266	CDD:275368	5/19 (26%)
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	24/64 (38%)
		zf-C2H2	311..333	CDD:278523	9/21 (43%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:290200	12/25 (48%)
		C2H2 Zn finger	341..362	CDD:275368	9/22 (41%)
		zf-H2C2_2	353..377	CDD:290200	7/23 (30%)
		zf-C2H2	368..390	CDD:278523	5/21 (24%)
		C2H2 Zn finger	370..390	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100