DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7691 and wor

DIOPT Version :9

Sequence 1:NP_650728.1 Gene:CG7691 / 42228 FlyBaseID:FBgn0038626 Length:283 Species:Drosophila melanogaster
Sequence 2:NP_476601.1 Gene:wor / 34906 FlyBaseID:FBgn0001983 Length:548 Species:Drosophila melanogaster


Alignment Length:383 Identity:91/383 - (23%)
Similarity:137/383 - (35%) Gaps:152/383 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 PRIFRSFLSD-------RYNGKQERFYDRYEDFCQVIPN----LPPMPRPKTNHHSRVATKPEPK 55
            |.|.::..||       .||....:....||| |..:.|    :||:|.|:..:       |.|.
  Fly   144 PTIIKAEPSDEEQFPLRNYNNNLLKSIAEYED-CMKMQNIKEEIPPIPSPQLFY-------PPPT 200

  Fly    56 TNVKFTYCFGQSEPSGDWRQGDDIPIVVRREMEERLGIQ-----LMSVL---------PI-TESS 105
            .         .:||       :|:.:..||.:.|.:.:|     |:|:.         || .|..
  Fly   201 P---------LAEP-------EDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHAPPPIDMEED 249

  Fly   106 LLSHTIWELKMPGESFDSIPKTRNGI-------------KVGIIT-------VTAESKQTRTKLK 150
            ..:..|.:||:         |:.|.:             ..|::.       .:.|.|..|::..
  Fly   250 QENQDINQLKI---------KSSNDLYYQCQQCNKCYATYAGLVKHQQTHAYESTEYKIIRSQPG 305

  Fly   151 RKGPIL----------------ANVTVPSNI---VEIPPI------------------QQRKMP- 177
            ..|.|:                |||....::   |.:|..                  ||...| 
  Fly   306 GSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFHCPS 370

  Fly   178 -EKRRLKRVGGQFECIDCD--------------------------KKFDHSWMLTAHTRTHTGEK 215
             |..::|:|   |.|.:||                          |.|...|:|..|.|||||||
  Fly   371 AEGNQVKKV---FSCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEK 432

  Fly   216 PFVCPDGSCRKAFSDRSNLRSHQRTMGHHE-WQHQCGQCGKYFSQFSYLNRHSLDACR 272
            ||.|.  .|.:||:||||||:|.:|  |.: .::.|..|.|.||:.|.|.:|....|:
  Fly   433 PFSCQ--HCNRAFADRSNLRAHMQT--HSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQ 486

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7691NP_650728.1 COG5048 188..>271 CDD:227381 39/109 (36%)
C2H2 Zn finger 191..211 CDD:275368 9/45 (20%)
zf-H2C2_2 203..229 CDD:290200 14/25 (56%)
C2H2 Zn finger 219..244 CDD:275368 12/24 (50%)
C2H2 Zn finger 250..266 CDD:275368 7/15 (47%)
worNP_476601.1 C2H2 Zn finger 270..290 CDD:275368 1/19 (5%)
C2H2 Zn finger 317..334 CDD:275368 3/16 (19%)
zf-C2H2 345..367 CDD:278523 2/21 (10%)
C2H2 Zn finger 347..367 CDD:275368 2/19 (11%)
PHA00732 379..>417 CDD:177300 7/40 (18%)
C2H2 Zn finger 382..402 CDD:275368 3/19 (16%)
zf-C2H2_8 405..482 CDD:292531 35/80 (44%)
zf-C2H2 406..428 CDD:278523 6/21 (29%)
C2H2 Zn finger 408..428 CDD:275368 6/19 (32%)
zf-H2C2_2 421..444 CDD:290200 14/24 (58%)
zf-C2H2 434..456 CDD:278523 13/25 (52%)
C2H2 Zn finger 436..456 CDD:275368 12/23 (52%)
zf-H2C2_2 448..473 CDD:290200 10/26 (38%)
C2H2 Zn finger 464..481 CDD:275368 7/16 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2462
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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