DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7691 and mazb

DIOPT Version :9

Sequence 1:	NP_650728.1	Gene:	CG7691 / 42228	FlyBaseID:	FBgn0038626	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	XP_001918976.1	Gene:	mazb / 100150156	ZFINID:	ZDB-GENE-110603-5	Length:	464	Species:	Danio rerio

Alignment Length:	263	Identity:	60/263 - (22%)
Similarity:	98/263 - (37%)	Gaps:	52/263 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PNLPP----MPRPKTNHHSRVATKPEPKTNVK--------FTYCFGQSEPSGDWRQGDDIPIVVR 84
            |..||    .|.|.|...:.:...|.|...|.        .:.|..|.:.|.:.|:...:...:|
Zfish    35 PQAPPTDHMAPPPSTVDTAALNEDPVPVKPVSRPARAAHICSICSKQFKNSYNLRRHQSVHTGIR 99

  Fly    85 ------------REMEERLGIQLMSVLPITESS--LLSHTIWELKMPGESFDSI-PKTRNGIKVG 134
                        ::..|:..: |:|:|.:.:.|  |...|:    ||.:....: |...|.:.:.
Zfish   100 MKTGAQNQEAQAKDSSEKHTV-LLSLLHLQQQSQTLPPPTV----MPAQHTQILAPPDGNDVAME 159

  Fly   135 IITVTAESKQTRTKLKRKGPILANVTVPSNIVEIPPIQQRKMPEKRRLKRVGGQFECIDCDKKFD 199
            .:..|.      |.|....|::.....|..    .|:.|...|.::       ...|..|.|.|.
Zfish   160 SVASTV------TALPPPPPVVMATGEPVQ----RPVNQNPNPVRK-------NHACETCGKAFR 207

  Fly   200 HSWMLTAHTRTHTGEKPFVCPDGSCRKAFSDRSNLRSHQRT-MGHHEWQHQCGQCGKYFSQFSYL 263
            ..:.|..|..:|:.||||.||  .|::.|..:..:..|.|: .|..|..:.|..|.|.||:..:|
Zfish   208 DVYHLNRHRLSHSDEKPFSCP--ICQQRFKRKDRMSHHVRSHQGGVEKPYVCPHCAKAFSRPDHL 270

  Fly   264 NRH 266
            |.|
Zfish   271 NSH 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7691	NP_650728.1	COG5048	188..>271	CDD:227381	27/80 (34%)
		C2H2 Zn finger	191..211	CDD:275368	6/19 (32%)
		zf-H2C2_2	203..229	CDD:290200	10/25 (40%)
		C2H2 Zn finger	219..244	CDD:275368	7/25 (28%)
		C2H2 Zn finger	250..266	CDD:275368	7/15 (47%)
mazb	XP_001918976.1	C2H2 Zn finger	75..95	CDD:275368	4/19 (21%)
		C2H2 Zn finger	199..219	CDD:275368	6/19 (32%)
		zf-H2C2_2	211..236	CDD:290200	11/26 (42%)
		C2H2 Zn finger	227..247	CDD:275368	6/21 (29%)
		C2H2 Zn finger	257..275	CDD:275368	8/17 (47%)
		C2H2 Zn finger	286..306	CDD:275368
		C2H2 Zn finger	312..331	CDD:275368
		C2H2 Zn finger	339..360	CDD:275368
		C2H2 Zn finger	382..402	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100