Protein Alignment fru and br

DIOPT Version :10

• Sequence 1: NP_001163648.1
• Gene: fru / 42226
• FlyBaseID: FBgn0004652
• Length: 960
• Species: Drosophila melanogaster
• Sequence 2: XP_061497249.1
• Gene: br / 3290570
• VectorBaseID: AGAMI1_003202
• Length: 688
• Species: Anopheles gambiae
• Alignment Length: 891
• Identity: 209/891 - (23%)
• Similarity: 312/891 - (35%)
• Gaps: 318/891 - (35%)

  Fly   109 QQFCLRWNNHPTNLTGVLTSLLQREALCDVTLACEGETVKAHQTILSACSPYFETIFLQNQHPHP 173
            |.|||||||:.:::|....:|...|...||||||:|.::|||:.:|||||.||..:.......||
Mosquito     5 QHFCLRWNNYQSSITSAFENLRDDEDFVDVTLACDGRSLKAHRVVLSACSTYFRELLKSTPCKHP 69

  Fly   174 IIYLKDVRYSEMRSLLDFMYKGEVNVGQSSLPMFLKTAESLQVRGLTDNN-----------NLNY 227
            :|.|:||.::::.:|::|:|.|||||.|.||..||||||.|:|.|||...           ..|.
Mosquito    70 VIVLQDVAFTDLHALVEFIYHGEVNVHQRSLSSFLKTAEILRVSGLTQQQAEETHGMHASLGANL 134

  Fly   228 RSDC-------DKLRDSAASSPTGRGP-----------SNYTGGLGGA---GGVADAMRESRDSL 271
            .|..       :|:.|.:.....|..|           |..:||:||.   ||.|..:
Mosquito   135 PSGVVHHPIYPEKMLDDSLYVSQGASPPPHLSSLHNSSSPNSGGVGGGNSNGGGAPMV------- 192

  Fly   272 RSRCERDLRDELTQRSSSSMSERSSAAAAAAAAAAAVAAAGGNVNAAAVAL---GLTTPTGGERS 333
                     ::|.:|              ||||||.......:|::..:||   .::..:.|..:
Mosquito   193 ---------NQLLKR--------------AAAAAALRRERNNSVHSDEMALKRHRMSVDSNGPTN 234

  Fly   334 PSVGSASAAAAAAAVAAAVAAAANRSASADGCSDRGSERGTLERTDSRDDLLQLD-YSNKDNNNS 397
            |            .....|..:..::.:.|..|....:..:|.....:|.:.|.| .|...|:.|
Mosquito   235 P------------RDHLDVICSTPQTTATDFSSSAAKQHLSLPSPQGKDQMRQQDSLSGHANSGS 287

  Fly   398 NSSSTGGNNN---NNNNNNNNSSSNNNNSSSN--RERNNSGERERERERERERDRDRELSTTPVE 457
            ||.|....:|   ::.|||||:.:||||.::|  ..:.|||
Mosquito   288 NSFSINSASNLIKSSINNNNNNINNNNNLNNNLLHSKENSG------------------------ 328

  Fly   458 QLSSSKRRRKNSSSNCDNSLSSSHQDRHYPQDSQANFKSSPVPKTGGSTSESEDAGGRHDSPLSM 522
                                                        .||.     .|||...|..||
Mosquito   329 --------------------------------------------VGGG-----GAGGLCGSGGSM 344

  Fly   523 TTSVHLG-GGGGNVGAASALSGLSQSLSIKQELMDAQQQQQHREHHVALPPDYLPSAALKLHAED 586
            .||  || ..|.|.|:                |..|:::.             |.|:..:..|||
Mosquito   345 PTS--LGTSNGSNAGS----------------LCSAEKES-------------LASSPSERSAED 378

  Fly   587 MST----LLT----QHALQAADARDEHNDAKQLQLDQTDNIDGRVKCFNIKHDRHPDRELDRNHR 643
            :.:    ||.    .|...:....|:|.|..:..||    :.|.::..|       |.||:.:..
Mosquito   379 VKSEPLELLCGTGGDHENSSDSVTDDHGDLVKGGLD----VKGSLRSPN-------DHELESSMH 432

  Fly   644 EHDD----------------------------DPGVIEEVVVDHVREME-AGNEHDPEEMKEAAY 679
            .|..                            ||..:.......::.:| ||:   |:.|..||.
Mosquito   433 HHSGAQFLMNASENKLFPTPPSFNFSMAALAADPSALAGFSTQALQAVELAGS---PQGMSIAAS 494

  Fly   680 HATPPKYRRAVVYAPPHPDEEAASGSGSDIYVDGGYN-------------CEYKCKELNMRAI-- 729
            .|...:      .|.|........|.||.::...|.|             |:...|.|:.:..
Mosquito   495 MAASQR------SASPPDGGGGGGGGGSSVHGGHGMNRLSLPLPLAACHRCDVCGKLLSTKLTLK 553

  Fly   730 RCSRQQHMMSHYSPHHPHHRSLIDCPAEAAYSPPVANNQAYLASNGAVQQLDLSTYHGHANHQ-- 792
            |...|||:.                        |: ||......:...:.|:....|....|:
Mosquito   554 RHKEQQHLQ------------------------PL-NNAVCNLCHKVFRTLNSLNNHKSIYHRRQ 593

  Fly   793 --LHQHPPSATHPSHSQSSPHYPSASGAGAGAGSVSVSIAGSASGSATSAPASVATSAVSPQPSS 855
              ||.|..:..||.|.|    :|.|.|.|.|||.     .|...|.          .||||....
Mosquito   594 KILHHHHHAHHHPLHGQ----HPFAVGGGPGAGG-----PGGGGGG----------GAVSPLHHG 639

  Fly   856 SSTGSTSSAAAVAAAAAA----------AANRRDHNIDYSTLFVQL 891
            ::..:.::||..||||||          ||...|.:|.::::..:|
Mosquito   640 AAHAAVTAAAVAAAAAAAGGHHELLNNNAAGATDCDIKHNSVAAKL 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fru	NP_001163648.1	BTB_POZ_BAB-like	135..218	CDD:349624	42/82 (51%)
		C2H2 Zn finger	901..918	CDD:275368
		C2H2 Zn finger	925..944	CDD:275368
br	XP_061497249.1	None