DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fru and ztf-25

DIOPT Version :9

Sequence 1:	NP_001163648.1	Gene:	fru / 42226	FlyBaseID:	FBgn0004652	Length:	960	Species:	Drosophila melanogaster
Sequence 2:	NP_507456.1	Gene:	ztf-25 / 180158	WormBaseID:	WBGene00012405	Length:	244	Species:	Caenorhabditis elegans

Alignment Length:	188	Identity:	39/188 - (20%)
Similarity:	66/188 - (35%)	Gaps:	44/188 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   718 EYKCKELNMRAIRCSRQQHMMSHYSPHHPHHRSLIDCPAEAAYSPPVANNQAYLASNGAVQQLDL 782
            |.|..:|..:.|..|..||...:.|.:  .||.|:.           .|....:..:..:...:.
Worm    15 ELKRPDLRGKFICASCGQHFQHNASLN--RHRRLLH-----------GNEHTCMMCDRKLNAKET 66

  Fly   783 STYHGHANHQLHQHPPSA----THPSHSQSSPHYPSASGAGAGAGSVSVSIAGSASGSATSAPAS 843
            ...|....|.|.|.....    :..|..|.|.|.....|.||...::.::       .:.:||.|
Worm    67 IRDHMRNEHNLFQVFTCGCCNWSFSSKRQLSEHTKCIQGTGAPGDTIPIA-------KSCNAPGS 124

  Fly   844 VATSAVSPQPSSSST-----GSTSSAAAVAAAAAAAANRRDHNIDYSTLFVQLSGTLP 896
            :..|.:...|....|     ||.||:::|:.:.::    ||           :||:.|
Worm   125 LIQSTIQGTPPVVKTGRKRGGSLSSSSSVSTSISS----RD-----------VSGSPP 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fru	NP_001163648.1	BTB	126..221	CDD:279045
		BTB	137..221	CDD:197585
		C2H2 Zn finger	901..918	CDD:275368
		C2H2 Zn finger	925..944	CDD:275368
ztf-25	NP_507456.1	COG5236	<22..>122	CDD:227561	20/119 (17%)
		C2H2 Zn finger	27..48	CDD:275368	7/22 (32%)
		C2H2 Zn finger	54..75	CDD:275368	1/20 (5%)
		C2H2 Zn finger	83..102	CDD:275368	4/18 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7558
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950