Protein Alignment CG10864 and Kcnk9

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_445857.2
• Gene: Kcnk9 / 84429
• RGDID: 621451
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 335
• Identity: 84/335 - (25%)
• Similarity: 133/335 - (39%)
• Gaps: 96/335 - (28%)

  Fly    60 YAICGAFAFMHIERQFVDETAGHVMELRQNCSQQLWSITEQHNIIDRRRWTEATNDVLREYQSQI 124
            |.:.||..|..:|       :.|.|...:....:...:..::||         ::|   :|| |:
  Rat    18 YLLVGAAVFDALE-------SDHEMREEEKLKAEEVRLRGKYNI---------SSD---DYQ-QL 62

  Fly   125 AGVVKHGYVGRSPEQIWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIPLYILYFL 189
            ..|:......|:..| |.|..:..|.::|||.||||:..|.|..||.|.:.||..||||.::.|.
  Rat    63 ELVILQSEPHRAGVQ-WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQ 126

  Fly   190 NMGRVLARSFKFLYRSLHDCTQEHPRLDRMDALEGGVGMTRKKVIVPS-----------TACLWV 243
            ::|..:....::|.:.:..|                .||...:|.:.:           |.||
  Rat   127 SLGERMNTFVRYLLKRIKKC----------------CGMRNTEVSMENMVTVGFFSCMGTLCL-- 173

  Fly   244 IFFYVLTGTVMFANWEKWSLLNSFYFCMTSLCKIGFGDFVPGASLTTSADVNAATQKLQEDISAD 308
                   |...|:..|.||..:::|:|..:|..|||||||
  Rat   174 -------GAAAFSQCEDWSFFHAYYYCFITLTTIGFGDFV------------------------- 206

  Fly   309 PAELAQLQSVAADQHSK--LAINFVYMLLGMGLVAMCRNLMREEVRLKAREMREDAKLCMEDTRL 371
                 .|||..|.|...  :|.:|:|:|:|:.::....||    |.|:...|..|..| :|....
  Rat   207 -----ALQSKGALQRKPFYVAFSFMYILVGLTVIGAFLNL----VVLRFLTMNTDEDL-LEGEVA 261

  Fly   372 RFVGCCGNPR 381
            :.:  .||||
  Rat   262 QIL--AGNPR 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	23/55 (42%)
		Ion_trans_2	242..>284	CDD:462301	14/41 (34%)
Kcnk9	NP_445857.2	Ion_trans_2	<73..132	CDD:462301	25/59 (42%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:Q9NPC2	93..98		3/4 (75%)
		Ion_trans_2	<184..243	CDD:462301	24/92 (26%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:Q9NPC2	199..204		3/4 (75%)
		X-gate. /evidence=ECO:0000250|UniProtKB:Q9NPC2	243..248		1/4 (25%)