Protein Alignment CG10864 and Kcnk10

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001303594.1
• Gene: Kcnk10 / 72258
• MGIID: 1919508
• Length: 538
• Species: Mus musculus
• Alignment Length: 329
• Identity: 79/329 - (24%)
• Similarity: 137/329 - (41%)
• Gaps: 83/329 - (25%)

  Fly    49 TQVGVGALIVIYAICGAFAFMHIERQFVDETAGHV-ME----LRQN-C--SQQLWSITEQHNIID 105
            |.|.:..::|:|.:.|...|..:|:.|.......: :|    ||.: |  .|:|.::. ||.:
Mouse    71 TVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHICVSPQELETLI-QHAL-- 132

  Fly   106 RRRWTEATNDVLREYQSQIAGVVKHGYVGRSPEQIWSFPAALMFCLSVITMIGYGNMVPRTPWGK 170
                 :|.|          |||...|....|... |...:|..|..:|||.|||||:.|.|..||
Mouse   133 -----DADN----------AGVSPVGNSSNSSSH-WDLGSAFFFAGTVITTIGYGNIAPSTEGGK 181

  Fly   171 GFTVIYATFGIPLYILYFLNMGRVLARSFKFLYRSLHDCTQEHPRLDRMDALEGGVGMTRKKVIV 235
            .|.::||.|||||:......:|..|...|             ...:.|::.:.....:::.|:.|
Mouse   182 IFCILYAIFGIPLFGFLLAGIGDQLGTIF-------------GKSIARVEKVFRKKQVSQTKIRV 233

  Fly   236 PSTACLWVIFFYVLTGTVMFAN--------WEKWSLLNSFYFCMTSLCKIGFGDFVPGASLTTSA 292
            .||      ..::|.|.::|..        .|.|:.|.|.||.:.:|..:||||||.|.    :|
Mouse   234 IST------ILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGG----NA 288

  Fly   293 DVNAATQKLQEDISADPAELAQLQSVAADQHSKLAINFVYMLLGMGLVAMCRNLMREEVRLKARE 357
            .:|                       ..:.:..|.  :.::|:|:...|...:::.:.:|:.:::
Mouse   289 GIN-----------------------YREWYKPLV--WFWILVGLAYFAAVLSMIGDWLRVLSKK 328

  Fly   358 MRED 361
            .:|:
Mouse   329 TKEE 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	25/55 (45%)
		Ion_trans_2	242..>284	CDD:462301	15/49 (31%)
Kcnk10	NP_001303594.1	Ion_trans_2	<150..206	CDD:462301	24/56 (43%)
		Ion_trans_2	244..323	CDD:462301	21/107 (20%)