Protein Alignment CG10864 and Kcnk13

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_071629.2
• Gene: Kcnk13 / 64120
• RGDID: 68941
• Length: 405
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 72/322 - (22%)
• Similarity: 120/322 - (37%)
• Gaps: 66/322 - (20%)

  Fly    53 VGALIVIYAICGAFAFMHIERQFVDETAGHVMELRQNCSQQLWSITEQHNIIDRRRWTEATNDVL 117
            :..||::|.:.||..|..:|       ....::.:|...::|.:.:..||:.     .|.....|
  Rat    23 LAGLILLYLLGGAAVFSALE-------LAQELQAKQRWEERLANFSRGHNLS-----REELRGFL 75

  Fly   118 REYQSQIAGVVKHGYVGRSPEQIWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIP 182
            |.|:.    ..|.|....|....|.|..|..|..:|:|.||:|...|.|..||.|.:.|...|..
  Rat    76 RHYEE----ATKAGIRMDSVRPRWDFTGAFYFVGTVVTTIGFGMTTPATTGGKVFLIFYGLIGCA 136

  Fly   183 LYILYFLNMGRVLARSFKFLYRSLHDCTQEHPRLDRMDALEGGVGMTRKKVIVPSTACLWVIFFY 247
            ..||:|......|.....::.|:.|     |.:|.|...:....|...:|....|.|......:|
  Rat   137 STILFFNLFLERLITVIAYVMRTCH-----HQQLRRRGTVARDNGKAPRKGEADSLAGWKPSVYY 196

  Fly   248 VLT------------GTVMFANWEKWSLLNSFYFCMTSLCKIGFGDFVPGASLTTSADVNAATQK 300
            |:.            .:.::...|.||..:|.|||..:...|||||.|             ::|.
  Rat   197 VMLILCLASVAISCGASALYTTMEGWSYFDSVYFCFVAFSTIGFGDLV-------------SSQN 248

  Fly   301 LQEDISADPAELAQLQSVAADQHSKLAINFVYMLLGMGLVAMCRN----LMREEVRLKAREM 358
            .|.:                ::.....:||.::|:|:..:....|    |:::.|....|::
  Rat   249 AQYE----------------NEGLYRFVNFFFILMGVCCIYSMFNVISILIKQTVNWILRKL 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	20/55 (36%)
		Ion_trans_2	242..>284	CDD:462301	14/53 (26%)
Kcnk13	NP_071629.2	Ion_trans_2	84..150	CDD:462301	21/65 (32%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	110..115		2/4 (50%)
		Ion_trans_2	203..285	CDD:462301	21/110 (19%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	237..242		3/4 (75%)