Protein Alignment CG10864 and Kcnk12

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: XP_038968799.1
• Gene: Kcnk12 / 64119
• RGDID: 68940
• Length: 521
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 99/499 - (19%)
• Similarity: 154/499 - (30%)
• Gaps: 211/499 - (42%)

  Fly     7 RKPSPGGTVGMGGGPSSVSSTPSNQPRKRVKR------CCRNFVTFMCTQVG----VGALIVIYA 61
            |.|.|                |..:.|:|:.|      |||.  :.:....|    :.|||.:|.
  Rat     4 RSPRP----------------PPRRCRRRLPRPSCCCCCCRR--SHLNEDTGRFVLLAALIGLYL 50

  Fly    62 ICGAFAFMHIERQFVDETAGHVMELRQNCSQQLWSITEQHNIIDRRRWTEATNDVLREYQSQIAG 126
            :.||..|..:      |:.|.. |.|......|.:.:..|.:.:     ......||.|::.:|.
  Rat    51 VAGATVFSAL------ESPGEA-EARARWGATLRNFSAAHGVAE-----PELRAFLRHYEAALAA 103

  Fly   127 VVKHGYVGRSPEQIWSFPAALMF-------------------------------CL--------- 151
            .|:...:  .|.  |.||.|..|                               |:
  Rat   104 GVRADAL--RPR--WDFPGAFYFVGTVVSTIDSQIPTAAVCRHPKADQFMHPRPCVQLLGLSQSR 164

  Fly   152 SVITMI---------------------------------------------------GYGNMVPR 165
            |:.||:                                                   |:|...|.
  Rat   165 SLATMLLKFQSSKLSTITPSTHWAFPVTPPLARGRGTSFRRRCCGCTWRLGLSVACPGFGMTTPA 229

  Fly   166 TPWGKGFTVIYATFGIPLYILYF-LNMGRVLARSFKFLYRSLHDCTQEHPR-------------- 215
            |..||.|.:.|..||....||:| |.:.|::: ...|:.|:   |.:...|
  Rat   230 TVGGKAFLIAYGLFGCAGTILFFNLFLERIIS-LLAFIMRA---CRERQLRRSGLLPATFRRGSA 290

  Fly   216 LDRMDALEGGVGMTRKKVIVPSTACLWVI--FFYVL---TGTVMFANWEKWSLLNSFYFCMTSLC 275
            |...|:|.|.         .||...:.:|  .|.||   ..:.|:.:.|.|..::|.|||..:..
  Rat   291 LSEADSLAGW---------KPSVYHVLLILGLFAVLLACCASAMYTSVEGWDYVDSLYFCFVTFS 346

  Fly   276 KIGFGDFVPGASLTTSADVNAATQKLQEDISADPAELAQLQSVAADQHSKLAINFVYMLLGMGLV 340
            .|||||.|   |...:|..|....:|.                          ||:::|||:..:
  Rat   347 TIGFGDLV---SSQHAAYRNQGLYRLG--------------------------NFLFILLGVCCI 382

  Fly   341 AMCRN----LMREEVRLKAREMREDAKLCMEDTRLRFVGCCGNP 380
            ....|    |:::.:....|::  ..:.|   ||     ||..|
  Rat   383 YSLFNVISILIKQVLNWMLRKL--SCRCC---TR-----CCPAP 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	24/147 (16%)
		Ion_trans_2	242..>284	CDD:462301	16/46 (35%)
Kcnk12	XP_038968799.1	Ion_trans_2	313..395	CDD:462301	27/110 (25%)