Protein Alignment CG10864 and KCNK15

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_071753.2
• Gene: KCNK15 / 60598
• HGNCID: 13814
• Length: 330
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 76/303 - (25%)
• Similarity: 123/303 - (40%)
• Gaps: 75/303 - (24%)

  Fly    47 MCTQVGVGALIVIYAICGAFAFMHIERQFVDETAGHVMELRQNCSQQLWSITEQHNIIDRRRWTE 111
            :||        :.|.:.||..|..:|.:            .::..|:|  :.::...: ||::..
Human    13 LCT--------LCYLLVGAAVFDALESE------------AESGRQRL--LVQKRGAL-RRKFGF 54

  Fly   112 ATNDVLREYQSQIAGVVKHGYVGRSPEQIWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIY 176
            :..| .||.:........|    |:..| |.||.:..|.::|||.|.||:..|.|..||.|.:.|
Human    55 SAED-YRELERLALQAEPH----RAGRQ-WKFPGSFYFAITVITTIEYGHAAPGTDSGKVFCMFY 113

  Fly   177 ATFGIPLYILYFLNMGRVLARSFKFLYRSLHDCTQEHPRLDRMDALEGGVGMTRKKVIVPSTACL 241
            |..||||.::.|.::|..|....:.|..:...|.          .|......|...|:....||.
Human   114 ALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCL----------GLRWTCVSTENLVVAGLLACA 168

  Fly   242 WVIFFYVLTGTVMFANWEKWSLLNSFYFCMTSLCKIGFGDFVPGASLTTSADVNAATQKLQEDIS 306
            ..:    ..|.|.|:::|.|:..:::|:|..:|..|||||||
Human   169 ATL----ALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFV----------------------- 206

  Fly   307 ADPAELAQLQSVAADQHS--KLAINFVYMLLGMGLVAMCRNLM 347
                   .|||..|.|..  .:|.:|:|:|||:.::....||:
Human   207 -------ALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLNLV 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	24/55 (44%)
		Ion_trans_2	242..>284	CDD:462301	14/41 (34%)
KCNK15	NP_071753.2	Ion_trans_2	<73..132	CDD:462301	25/59 (42%)
		Ion_trans_2	177..243	CDD:462301	26/96 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..276