Protein Alignment CG10864 and twk-43

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_872137.2
• Gene: twk-43 / 3565024
• WormBaseID: WBGene00006693
• Length: 597
• Species: Caenorhabditis elegans
• Alignment Length: 341
• Identity: 86/341 - (25%)
• Similarity: 134/341 - (39%)
• Gaps: 104/341 - (30%)

  Fly    52 GVGALIVIYAICGAFAFMHIER--QFVDETAGHVMELRQNCSQQLWSITEQHNIIDRRRWTEATN 114
            |:...:.||...||....:|||  ..|:|:    ..||:|....:       .||...|..|...
 Worm    43 GIVLFVGIYVYAGALLIQYIERIPVKVEES----FRLRRNSQDDM-------PIIPLDRSKECVL 96

  Fly   115 DVLREYQSQIA-----------GVVKHGYV---------------GRSPEQ-------------- 139
            ..||: .|||:           .::::.|.               .::|||
 Worm    97 QALRK-MSQISKGNCSQLHNNVNLLENCYASDLQKLKTIYDSSEGSKAPEQQSAVALKKFVIVDG 160

  Fly   140 --IWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIPLYILYFLNMGRVLARSFKFL 202
              .|:...|::||.:|||.|||||:.|::.||:.|.:||.|.|||..::...|:|:.||...|..
 Worm   161 FEQWTTTDAILFCFTVITTIGYGNVAPQSFWGRVFVIIYGTIGIPTAMMAIANVGKFLATLLKSW 225

  Fly   203 YRS-LHDCTQEHPRLDRMDALEGGVGMTR----------KKV-------------------IVPS 237
            .|. |..|.:...|:.:.|.....:..|:          ||:                   .|..
 Worm   226 TRPFLLLCRKMKKRMQKKDQNGNEIKETQRLMESSKKKAKKIEDDISSHEDEEAEEEVEESDVTE 290

  Fly   238 TACLWVIFF-YVLTGTVMFANWEKWSLLN-SFYFCMTSLCKIGFGDFVP---------------G 285
            |..|:|.|. |::.|:::.:.:|:..... :.||...:|..||.||.||               |
 Worm   291 TIVLFVAFLVYIIAGSLLMSYYEEGMTFGLAIYFNFVTLTTIGLGDLVPQSTDWLFVTLVYCAIG 355

  Fly   286 ASLTTSA-DVNAATQK 300
            .:|||.| ::.|.|.|
 Worm   356 LALTTIAIEIAADTLK 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	25/55 (45%)
		Ion_trans_2	242..>284	CDD:462301	12/43 (28%)
twk-43	NP_872137.2	Ion_trans_2	155..218	CDD:462301	24/62 (39%)
		Ion_trans_2	298..372	CDD:462301	21/74 (28%)