Protein Alignment CG10864 and twk-13

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001122984.1
• Gene: twk-13 / 192077
• WormBaseID: WBGene00006668
• Length: 625
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 105/495 - (21%)
• Similarity: 167/495 - (33%)
• Gaps: 191/495 - (38%)

  Fly     3 SKFQR--KP-SPGGTVGMGGGPSSV-------SSTPSNQPRK----------------------- 34
            |.|||  :| |||.::|....|.|:       |:|..:|...
 Worm    25 SSFQRHHRPSSPGISLGPPSSPPSLYNLQQIASATGVDQQNNDVEELSAERLNLYLDKEEGEIEN 89

  Fly    35 ---------------RVKRCCRNFVTFMCTQVGVGALIVIYAICGAFAFMHIER----QFVDETA 80
                           |.||..|    ......|:..|.:.|.:.||..|.|.|:    |..:||:
 Worm    90 LEEEIDETTEKKWWLRTKRWFR----LALPHFGLVLLSIGYTLIGALCFHHYEKPYEQQLRNETS 150

  Fly    81 GHVMELRQNCSQQLWSITEQHNIIDRRRWTEATNDVLREYQSQIAGVVKHGYVGRSPEQI----- 140
            ..:.||:.....|||.::  :|......|.:..||.:.|....:.......|:  :|:.:
 Worm   151 RRIGELKNRVMDQLWRMS--NNGTAYSTWRQTANDGMDELIRDVFWDYTRNYM--TPDDVIYGDG 211

  Fly   141 ---WSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIPLYILYFLNMGRVLA------ 196
               |||.:::.|..:.||.||||::||||..|:...:.||..||||.::...::||.||
 Worm   212 PIKWSFMSSIFFSWTAITTIGYGHIVPRTDEGRVAIIFYALLGIPLILVTIADIGRFLATYIIKL 276

  Fly   197 -----RSFKFLYRSLHDC----------TQEHPRLDRMDALE----------------------G 224
                 ....|:..|...|          .:.|..:..::.|:                      |
 Worm   277 HHGYMAVMSFVTNSCLKCIKWACCWIRLPRRHIPMPTLELLQRTQKLYPNNNNPTVAATAASAGG 341

  Fly   225 GVGMTRKK------------------------------------VIVPS-----TACLWVIFF-- 246
            |.|..:|:                                    ...||     .:.|:::..
 Worm   342 GTGRRKKQQRDNVSDAGTFDNISEINDGSEGGENENEGEEEEQIQFDPSNHEKRVSVLFILLIML 406

  Fly   247 -YVLTGTVMFANWEKWSLLNSFYFCMTSLCKIGFGDFVPGASLTTSADVNAATQKLQEDISADPA 310
             ||..|..:...||:|:...:||||..::..|||||.||.                  ::...||
 Worm   407 GYVAGGAYIVRWWEEWTFFEAFYFCFVTVTTIGFGDIVPA------------------NVDWLPA 453

  Fly   311 ELAQLQSVAADQHSKLAINFVYMLLGMGLVAMCRNLMREE 350
            .||                  |::.|:.:..||.:|:..|
 Worm   454 TLA------------------YIVFGLIITTMCIDLVGSE 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	25/66 (38%)
		Ion_trans_2	242..>284	CDD:462301	15/44 (34%)
twk-13	NP_001122984.1	Ion_trans_2	<214..269	CDD:462301	23/54 (43%)
		Ion_trans_2	401..478	CDD:462301	27/111 (24%)