Protein Alignment CG10864 and twk-12

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_505731.3
• Gene: twk-12 / 192074
• WormBaseID: WBGene00006667
• Length: 684
• Species: Caenorhabditis elegans
• Alignment Length: 350
• Identity: 78/350 - (22%)
• Similarity: 142/350 - (40%)
• Gaps: 74/350 - (21%)

  Fly    34 KRVKRCC-----RNFVTFMCTQVGVGALIVIYAICGAFAFMHIERQFVD----ETAGHVMELRQN 89
            |:::..|     |::..|:        |::.|...||:.|...|.| .|    ...|:...|.:.
 Worm     5 KKIQWFCNLIRLRSYYKFL--------LLIAYTAFGAWLFRTYELQ-ADIKRRSVFGNTTNLVRR 60

  Fly    90 CSQQLW------SITEQHNIIDRRRWTEATNDVLREYQSQIAGVVKHGYVGRSPEQIWSFPAALM 148
            ...:.|      ::....:.:..||..||...:|.|.  .::..::    ..|.|..|::..|:.
 Worm    61 QLAERWIEMHKDAVLRNDSALRFRRAAEAVEWLLDEL--NLSDHIR----DLSEETPWTWTGAMF 119

  Fly   149 FCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIPLYILYFLNMGRVLARSFKFLYRSLHDCTQEH 213
            :...:.|.||||....:|..|:..|:.||.||||.:::|..::|:.|::..|..|:.|.......
 Worm   120 YAGQLYTTIGYGYPTTKTDEGRICTIFYALFGIPCFLMYLKSIGKTLSKKMKKYYKKLRRSRVGR 184

  Fly   214 PRL-DRMDALEGG-----VGMTRKKVIVPSTACLWVIFFYVLTGTVMFANWE-KWSLLNSFYFCM 271
            ..| .|:.|::.|     ....|||...|....:.::..::.....||..|| .|...::.||.:
 Worm   185 ILLPTRVTAMKDGFEDPEAAEERKKKPFPIPIAIIMLIIWICFSASMFCIWEDTWVFSSAVYFFI 249

  Fly   272 TSLCKIGFGDFVPGASLTTSADVNAATQKLQEDISADPAELAQLQSVAADQHSKLAINFVYMLLG 336
            .|:..:|.||.     |..:.|:                               :..||:.:|:|
 Worm   250 VSISTVGLGDM-----LFRTPDM-------------------------------MVFNFLLILVG 278

  Fly   337 MGLVAMCRNLMREEVRLKAREMRED 361
            :.|::||..|:.:.| .|.::.|.|
 Worm   279 LALLSMCFELITDRV-AKWKQKRFD 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	19/55 (35%)
		Ion_trans_2	242..>284	CDD:462301	11/42 (26%)
twk-12	NP_505731.3	Ion_trans_2	92..167	CDD:462301	22/80 (28%)
		Ion_trans_2	226..>272	CDD:462301	13/81 (16%)