Protein Alignment CG10864 and twk-45

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001122742.2
• Gene: twk-45 / 190614
• WormBaseID: WBGene00006695
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 289
• Identity: 66/289 - (22%)
• Similarity: 128/289 - (44%)
• Gaps: 55/289 - (19%)

  Fly    33 RKRVKRCCRNFVT------------FMCTQVGVGALIVIYAICGAFAFMHIER----QFVDETAG 81
            ::|.|:..|..:|            |....:.:.:::..|...|.|.|..:|.    :.:.||..
 Worm    57 KERKKQIRREKITWFFAWLAYYHHKFGIRHITLISILAAYICLGGFLFQKLESPREIEELQETLK 121

  Fly    82 HVMELRQNCSQQLWSITEQHNIIDRRRWTEATNDVLREY-------QSQIAGVVKHGYVGRSPEQ 139
            .:.|:.:|.:..:..||...|..||   .:...|:||.|       :.:..|...|.........
 Worm   122 SMNEIIKNETMDIIKITLTTNGEDR---NQKLGDLLRAYHRILLETEGKFHGSAWHKSENLDMNL 183

  Fly   140 IWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIPLYILYFLNMG----RVLARSFK 200
            :|.|.:|..:.:::.:.||||.:..:|.|||..:::||:.|:|:.:|...::|    :|:..::.
 Worm   184 MWYFSSATFYSMTLFSTIGYGTITCQTFWGKTVSMVYASIGLPIMLLVLGDIGVWFQKVMTNAYI 248

  Fly   201 FL---YRSLHDCTQEHPRLDRMDALEGGVGMTRKKVIVPSTACLWVIFFYVLTGTVMFANWEK-- 260
            |:   |:||           |..::|    :.||:.::|....:.|:|.|::..|:....::.
 Worm   249 FVMLKYKSL-----------RKQSIE----IKRKETLLPMWLAMLVVFTYIIICTLTILLFDDNE 298

  Fly   261 -----WSLLNSFYFCMTSLCKIGFGDFVP 284
                 .:..::|||...||..||.||.:|
 Worm   299 GDEPGINFFDAFYFTFISLTTIGLGDVMP 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	18/59 (31%)
		Ion_trans_2	242..>284	CDD:462301	13/48 (27%)
twk-45	NP_001122742.2	Ion_trans_2	179..241	CDD:462301	17/61 (28%)
		Ion_trans_2	278..354	CDD:462301	14/50 (28%)