Protein Alignment CG10864 and twk-20

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_510284.1
• Gene: twk-20 / 181485
• WormBaseID: WBGene00006673
• Length: 364
• Species: Caenorhabditis elegans
• Alignment Length: 343
• Identity: 88/343 - (25%)
• Similarity: 131/343 - (38%)
• Gaps: 126/343 - (36%)

  Fly    55 ALIVI-----YAICGAFAFMHIERQFVDETAGHVMELRQNCSQQLWSITEQHNIIDRRRWTEATN 114
            ||::|     |.:.||..|..:|.:                 :..|...|...|.||
 Worm    11 ALLLILSTFTYLLFGAMVFDKLESE-----------------KDTWVRDEIERITDR-------- 50

  Fly   115 DVLREYQSQIAGVVKHGY--------------VGRSPEQI---WSFPAALMFCLSVITMIGYGNM 162
                         :||.|              :...|:|.   |.|..|..|...|||.:|||:.
 Worm    51 -------------LKHKYNFSERDLHLFEAIAIKSIPQQAGYQWQFAGAFYFATVVITTVGYGHS 102

  Fly   163 VPRTPWGKGFTVIYATFGIPLYILYFLNMG-RV---LARSFKFLYRSLHD----CTQEHPRLDRM 219
            .|.|..||.|.:|:|.||:|:.::.|.::| ||   :|.|......|||.    |.||
 Worm   103 APSTNAGKLFCMIFALFGVPMGLIMFQSIGERVNTFIAYSLHKFRDSLHQQGFTCLQE------- 160

  Fly   220 DALEGGVGMTRKKVIVPSTACLWVIFFYVLTGTVMFANWEKWSLLNSFYFCMTSLCKIGFGDFVP 284
                    :|...:::.|   |.:.|..:::||.||...||||:.:::||||.:...|||||.||
 Worm   161 --------VTPTHLLMVS---LTIGFMVIVSGTYMFHTIEKWSIFDAYYFCMITFSTIGFGDLVP 214

  Fly   285 GASLTTSADVNAATQKLQEDISADPAELAQLQSVAADQHSKLAI--NFVYMLLGMGLVAMCRNLM 347
                                          ||.|.|.|...|.:  ..:::|:|:.:.:.|.||:
 Worm   215 ------------------------------LQQVNALQDQPLYVFATIMFILIGLAVFSACVNLL 249

  Fly   348 --------REEVRLKARE 357
                    .:||....||
 Worm   250 VLGFMASNADEVTAAQRE 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	24/59 (41%)
		Ion_trans_2	242..>284	CDD:462301	18/41 (44%)
twk-20	NP_510284.1	Ion_trans_2	<78..135	CDD:462301	22/56 (39%)
		Ion_trans_2	175..250	CDD:462301	31/104 (30%)