Protein Alignment CG10864 and twk-44

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_509942.4
• Gene: twk-44 / 181349
• WormBaseID: WBGene00006694
• Length: 733
• Species: Caenorhabditis elegans
• Alignment Length: 329
• Identity: 78/329 - (23%)
• Similarity: 128/329 - (38%)
• Gaps: 92/329 - (27%)

  Fly    70 HIERQFVDETAGHVMELRQNCSQQL----WSI-TEQHNIIDRRRWTE-----ATNDVLREYQSQI 124
            |.|..|     |.:..|: |.::||    |.: .|..|    :.||.     ..|..:.||.:.:
 Worm   190 HFESNF-----GRIRALK-NYTEQLCLRCWELGVEGAN----QGWTRYNYSLMVNQSVEEYNNSV 244

  Fly   125 AGVVKHGYVGRSPEQIWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYATFGIPLYILYFL 189
            .       :|.....:|:|..|:...::..|.|||||:..:|..||...::||..||||.::...
 Worm   245 G-------LGHVLTPVWTFWNAMFLAVTTYTTIGYGNITAKTKLGKLAAMVYAVVGIPLVLMILH 302

  Fly   190 NMGRVLARSFKFLYRSLHDCTQEHPRLDRMDALEGGVGMTRKKVI-------VPSTACLWVIFFY 247
            ..||:.....:.::..:...|         |:...|.|..|.:..       :|....:.|.|.:
 Worm   303 KSGRLFLMGLEHMWDFILRIT---------DSFCVGSGKQRVRNTGEDRISEMPLILAIGVAFGW 358

  Fly   248 VLTGTVMFANWEK-WSLLNSFYFCMTSLCKIGFGDFVPGASLTTSADVNAATQKLQEDISADPAE 311
            :.....:|..:|| |....||||...||..||:||..|    |.|.|
 Worm   359 MFLCAAIFLRFEKDWDYFKSFYFFFCSLTTIGYGDVTP----TNSED------------------ 401

  Fly   312 LAQLQSVAADQHSKLAINFVYMLLGMGLVAMCRNLMREEVRLKAREMREDAKLCM--------ED 368
                          :.|.|..:::|:.||:||.|:    ::||..::.|:..|.:        :.
 Worm   402 --------------MFIIFGLIIIGLSLVSMCINV----IQLKLEKLFEELLLTLMEELNADPDG 448

  Fly   369 TRLR 372
            |||:
 Worm   449 TRLK 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	20/55 (36%)
		Ion_trans_2	242..>284	CDD:462301	16/42 (38%)
twk-44	NP_509942.4	Ion_trans_2	<254..308	CDD:462301	20/53 (38%)
		Ion_trans_2	354..>397	CDD:462301	17/46 (37%)