Protein Alignment CG10864 and twk-34

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_506906.3
• Gene: twk-34 / 180054
• WormBaseID: WBGene00006686
• Length: 558
• Species: Caenorhabditis elegans
• Alignment Length: 321
• Identity: 74/321 - (23%)
• Similarity: 121/321 - (37%)
• Gaps: 55/321 - (17%)

  Fly     3 SKFQRKPSPGGTVGMGGGPS----SVSSTPS--NQPRKRVKRCCRNF------VTFMCTQVG--- 52
            |.|||.....|.:.....|.    ||.|:|.  .:|   |....|:|      ..|...|:|
 Worm   105 SGFQRNQDTFGQLQRRYKPRQDAISVLSSPGALGEP---VMPTDRHFDRSMYWFAFHRKQIGLRH 166

  Fly    53 --VGALIVIYAICGAFAFMHI----ERQFVDETAGHVMELRQNCSQQLWSITEQHNIIDRRRWTE 111
              |..:::.|.|.|||.|..:    ||....|...::..|....:..:..|....|...    ||
 Worm   167 IMVALMVLSYTIFGAFMFWTVESRNERAVTLERVTNLENLLNILATNITEIVNNPNTTT----TE 227

  Fly   112 ATNDV--------LREYQSQIAGVVKHGYVGRSPEQIWSFPAALMFCLSVITMIGYGNMVPRTPW 168
            |...|        |.:.:.|..|...:..........|:|.:|..|.::|.|..|||::.|.:..
 Worm   228 AEMQVYIREAYVSLMKLEGQYKGSTYYKLEDHGKNWKWTFESAFFFSMNVYTTTGYGSIAPESIL 292

  Fly   169 GKGFTVIYATFGIPLYILYFLNMGRVLARSFKFLYRSLHDCTQEHPRLDRMDALEGGVGMTRKKV 233
            |:....:|....:|:.::...::|:........||..|         :.|...:.|...:...::
 Worm   293 GQVLVCLYGFIFVPVTLVALRDLGQFFLVHLTKLYAQL---------IQRWREINGDTSIDVNEI 348

  Fly   234 I-VPSTACLWVIFFYVLTGTVMFANWEK---------WSLLNSFYFCMTSLCKIGFGDFVP 284
            | :|..|||.::..|:...|:....:::         .|:...|||...||..||.||.:|
 Worm   349 IKIPIKACLLLLALYLAFCTIFIHVFDELSGDESGSGMSVFLCFYFSFISLSTIGLGDIMP 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	14/55 (25%)
		Ion_trans_2	242..>284	CDD:462301	12/50 (24%)
twk-34	NP_506906.3	Ion_trans_2	250..319	CDD:462301	15/68 (22%)
		Ion_trans_2	366..442	CDD:462301	12/44 (27%)