Protein Alignment CG10864 and KCNK7

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_203133.1
• Gene: KCNK7 / 10089
• HGNCID: 6282
• Length: 307
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 80/330 - (24%)
• Similarity: 124/330 - (37%)
• Gaps: 76/330 - (23%)

  Fly    54 GALIVIYAIC---GAFAFMHIERQFVDETAGHVMELRQNCSQQLWSITEQHNIIDRRRWTEATND 115
            |.|:|.:.:.   ||..|..:|       ......|:.....:|.:...:|...       ....
Human    11 GLLVVAHLLALGLGAVVFQALE-------GPPACRLQAELRAELAAFQAEHRAC-------LPPG 61

  Fly   116 VLREYQSQIAGVVKHGY--VGRSPE-QIWSFPAALMFCLSVITMIGYGNMVPRTPWGKGFTVIYA 177
            .|.|..........||.  :|.|.| :.|..|:||:|..|::|..|||:|.|.:|.||.|.::||
Human    62 ALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYA 126

  Fly   178 TFGIPLYILYFLNMGR----VLARSFKFLYRSLHDCTQEHP-RLDRMDALEGGVGMTRKKVIVPS 237
            ..|:|..:.....:..    ||:|...::  ::|  .|..| |...:.|:..|:.:....|::|:
Human   127 ALGLPASLALVATLRHCLLPVLSRPRAWV--AVH--WQLSPARAALLQAVALGLLVASSFVLLPA 187

  Fly   238 TACLWVIFFYVLTGTVMFANWEKWSLLNSFYFCMTSLCKIGFGDFVPGASLTTSADVNAATQKLQ 302
            .. ||     .|.|..        |||.:.|||.:||..||..|.:||...
Human   188 LV-LW-----GLQGDC--------SLLGAVYFCFSSLSTIGLEDLLPGRGR-------------- 224

  Fly   303 EDISADPA--ELAQLQSVAADQHSKLAINFVYMLLGMGLVAMCRNLMRE--EVRLKAREMREDAK 363
               |..|.  .|.||..:.            |:|||:..:.:......|  :||...:..|....
Human   225 ---SLHPVIYHLGQLALLG------------YLLLGLLAMLLAVETFSELPQVRAMGKFFRPSGP 274

  Fly   364 LCMED 368
            :..||
Human   275 VTAED 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	22/59 (37%)
		Ion_trans_2	242..>284	CDD:462301	14/41 (34%)
KCNK7	NP_203133.1	Ion_trans_2	84..140	CDD:462301	22/55 (40%)