Protein Alignment CG10864 and kcnk12

DIOPT Version :10

• Sequence 1: NP_650726.1
• Gene: CG10864 / 42222
• FlyBaseID: FBgn0038621
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: XP_002935426.2
• Gene: kcnk12 / 100494329
• XenbaseID: XB-GENE-1012003
• Length: 428
• Species: Xenopus tropicalis
• Alignment Length: 326
• Identity: 76/326 - (23%)
• Similarity: 131/326 - (40%)
• Gaps: 80/326 - (24%)

  Fly    34 KRVKRCC------RNFVTFMCTQVGVGALIVIYAICGAFAFMHIERQFVDETAGHVMELRQNCSQ 92
            :|.|.||      .:...|:...|    .|::|.|.||..|..|||.  .|...|.   |.|...
 Frog     5 RRTKTCCCLLPLNEDNGRFLLLAV----FILLYLIAGATVFSTIERP--SEALAHT---RWNTIL 60

  Fly    93 QLWSITEQHNIIDRRRWTEATNDVLREYQSQIAGVVKHGYVGRSPEQIWSFPAALMFCLSVITMI 157
            :.:|.:...::::.|.:       |::|::.:|..::...:  .|.  |.|..|..|..:|::.|
 Frog    61 RNFSHSFNISVLELRSF-------LKDYEAAMAAGIRADAL--RPR--WDFTGAFYFVGTVVSTI 114

  Fly   158 GYGNMVPRTPWGKGFTVIYATFGIPLYILYF-LNMGRVLARSFKFLYRSLHD-----------CT 210
            |:|...|.|..||.|.:.|..||....||:| |.:.|::: ...|:.::.|:           ..
 Frog   115 GFGMTTPATITGKVFLIFYGLFGCAGTILFFNLFLERIIS-LLAFVMKACHERRLRRSGLLPPTV 178

  Fly   211 QEHPRLDRMDALEGGVGMTRKKVIVPSTACLWVIFFYVLT--GTVMFANWEKWSLLNSFYFCMTS 273
            :....:..:|:|.|.      |..|.....:..||..:|:  .:.|:...|.|:.::|.|:|..:
 Frog   179 RRGSAVSEVDSLVGW------KPSVYHVMLILGIFAIILSCCASAMYTPVEGWNYIDSLYYCFVT 237

  Fly   274 LCKIGFGDFVPGASLTTSADVNAATQKLQEDISADPAELAQLQSVAADQHSKLAI--NFVYMLLG 336
            ...|||||.|...:                               |..|:..|..  ||:::|||
 Frog   238 FSTIGFGDLVSSQN-------------------------------AVYQYQGLYRFGNFMFILLG 271

  Fly   337 M 337
            :
 Frog   272 V 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10864	NP_650726.1	Ion_trans_2	<141..197	CDD:462301	21/56 (38%)
		Ion_trans_2	242..>284	CDD:462301	14/43 (33%)
kcnk12	XP_002935426.2	Ion_trans_2	86..153	CDD:462301	23/70 (33%)
		Ion_trans_2	206..288	CDD:462301	23/98 (23%)