Protein Alignment MEOX1 and HHEX

DIOPT Version :10

• Sequence 1: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 266
• Identity: 72/266 - (27%)
• Similarity: 102/266 - (38%)
• Gaps: 46/266 - (17%)

Human    11 SLQPPAPVWGCLRNPHS----EGNGASGLPHYPPTPFSFHQKPDFLATATAAYPDFSASCLAA-- 69
            |.|.|..|...:..||:    :.:.|:|.....|||     .|   ::||..| |.|....||
  Fly    33 SSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTP-----SP---SSATNIY-DLSREAAAAQY 88

Human    70 -----------TPHSL------PQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMG 117
                       .|.||      |....:|.:|.....::|:...|...|.....:.....:....
  Fly    89 AMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCD 153

Human   118 TSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQ 182
            ..|...:|..|.|        :.|:............:|....|.|......:.|     ||.:|
  Fly   154 QYSPFTMDCEGFP--------NPASAAAALYCNAYPAASFYMSNFGVKRKGGQIR-----FTSQQ 205

Human   183 LRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQDPEDGDS 247
            .:.|||.||...||:...|..:|:.|.|::||||.||||||.||:|....:. |.:.|.|..|.:
  Fly   206 TKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKR-SASAQGPIAGAA 269

Human   248 TASPSS 253
            ..||||
  Fly   270 VGSPSS 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		12/91 (13%)
		Homeodomain	172..228	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		9/27 (33%)
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	27/55 (49%)