Protein Alignment MEOX1 and Hmx

DIOPT Version :10

• Sequence 1: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 71/247 - (28%)
• Similarity: 108/247 - (43%)
• Gaps: 43/247 - (17%)

Human    11 SLQPPAPVWGCLRNP-HS--EGNGASGLPHYPPTPFSF-----HQKPDFLATATAAYPDFSASCL 67
            :|.||...|...|.| ||  ..:.::.....||:|.|.     :...:..|::..|....|...|
  Fly   293 ALCPPGWPWAPQRLPFHSPTHDSSSTNTTENPPSPTSMSPNNNNNNSNTTASSNQASKSPSHHPL 357

Human    68 AATPHSL----------PQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSL- 121
            ....|.|          ..::|...:|||...|..:.|.|.:         |...|...|.|||
  Fly   358 HPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPHQPTT---------PTSSSSSGGGSSLT 413

Human   122 -----GLVDTTGGPGDDYGVLGSTANETEKKSSR--RRKESSDNQENRGKPEG---SSKARKERT 176
                 .|..:.||    | :|.|::||::::...  ...:.:|...:...|.|   |.:.:|.||
  Fly   414 HHPHPHLTGSHGG----Y-LLPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGDGNSKRKKKTRT 473

Human   177 AFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKR 228
            .|::.|:.:||:.|....||:...|..:|.:|.|:|.|||:||||||.||||
  Fly   474 VFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		25/102 (25%)
		Homeodomain	172..228	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		2/2 (100%)
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	26/55 (47%)