Protein Alignment MEOX1 and Dfd

DIOPT Version :10

• Sequence 1: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 82/342 - (23%)
• Similarity: 113/342 - (33%)
• Gaps: 150/342 - (43%)

Human    24 NPHSEGNG-ASGLPHYPPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSLPQEEHIFTEQHP- 86
            ||||..:. ...|||:       |..........|:...:|::...|||   |...|.....||
  Fly    95 NPHSHSHSHTHSLPHH-------HSNSAISGHHQASAGGYSSNYANATP---PSHPHSHPHAHPH 149

Human    87 -----------------AFPQSP-NWHFPVSDARRRPNSGPAGGS------KEMGTSSLGLVDTT 127
                             |....| |.:.|.::.....|.|..|||      ..:|.|:.|..
  Fly   150 QSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYY--- 211

Human   128 GGPGDDYGV----LGST-----------------ANETEK-------------KSSRRRKE---- 154
            ||.|..||.    :|||                 .:.||.             |..:|.:|
  Fly   212 GGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPA 276

Human   155 ---------------------------------------SSDNQENRGKPEGSS----------- 169
                                                   |:||.::.|..:...
  Fly   277 GQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGER 341

Human   170 -----------------------KARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLS 211
                                   :.:::|||:|:.|:.|||.||.::.||||.||.|||..|.||
  Fly   342 IIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLS 406

Human   212 ERQVKVWFQNRRMKWKR 228
            |||:|:||||||||||:
  Fly   407 ERQIKIWFQNRRMKWKK 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		32/227 (14%)
		Homeodomain	172..228	CDD:459649	35/55 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		1/2 (50%)
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	35/55 (64%)