Protein Alignment MEOX1 and bcd

DIOPT Version :10

• Sequence 1: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_788587.1
• Gene: bcd / 40830
• FlyBaseID: FBgn0000166
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 216
• Identity: 59/216 - (27%)
• Similarity: 80/216 - (37%)
• Gaps: 48/216 - (22%)

Human    39 PPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARR 103
            ||...:|:..| ...|.|..:|.....     |||.|...|    |||.....|.:..|.
  Fly     4 PPPDQNFYHHP-LPHTHTHPHPHSHPH-----PHSHPHPHH----QHPQLQLPPQFRNPF----- 53

Human   104 RPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGS 168
                            .|...:.||....:| :.....|:..|......:|..|:...|
  Fly    54 ----------------DLLFDERTGAINYNY-IRPYLPNQMPKPDVFPSEELPDSLVMR------ 95

Human   169 SKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWK------ 227
             :.|:.||.||..|:.|||..|....|||..|..:::..|.|...|||:||:|||.:.|
  Fly    96 -RPRRTRTTFTSSQIAELEQHFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRRHKIQSDQH 159

Human   228 --RVKGGQPISPNGQDPEDGD 246
              :...|.|:|| |....|||
  Fly   160 KDQSYEGMPLSP-GMKQSDGD 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		15/91 (16%)
		Homeodomain	172..228	CDD:459649	25/63 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		9/28 (32%)
bcd	NP_788587.1	Homeodomain	106..153	CDD:459649	19/46 (41%)