Protein Alignment MEOX1 and exex

DIOPT Version :10

• Sequence 1: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 74/265 - (27%)
• Similarity: 106/265 - (40%)
• Gaps: 73/265 - (27%)

Human    24 NPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYPDFSASCL-AATPHSLPQEEHI---FTEQ 84
            :|..:|...|      .:|.|.|:          :.|..|..|. ...||.....:|:   .::.
  Fly   299 SPSPDGMSRS------ESPTSSHR----------SSPPISPGCEDQQQPHGALHPQHLSMRMSDF 347

Human    85 HPAFPQSPNWHFPVSDARRRPNSGP--AGGS-----KEMGTSSLGLVDTTGGP-----GDDY--- 134
            |..|.:....|.|:     ||...|  |||.     .:.|::....:|.:|.|     |.::
  Fly   348 HDEFKKPIPPHSPI-----RPQDFPLYAGGHPYQLLAQGGSAFHRPLDPSGKPIPIPMGHNFMPS 407

Human   135 ----------GVLGSTANETEKKSSRRRKESSDNQENRGKPEGS--SKARKERTAFTKEQLRELE 187
                      |:|.....|.                 ...|..:  .|.|:.|||||.:||.|||
  Fly   408 QLQFEFLARAGMLHHRIPEL-----------------AAYPHHAILGKTRRPRTAFTSQQLLELE 455

Human   188 AEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPN----GQDPEDGDST 248
            .:|..:.||:|.:|:|:|..|.|||.|||:|||||||||||.|..|..:..    .|..:....|
  Fly   456 KQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKKAQQEAKERAKANQQQQQQQQT 520

Human   249 ASPSS 253
            .|.:|
  Fly   521 PSAAS 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		22/118 (19%)
		Homeodomain	172..228	CDD:459649	34/55 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		8/31 (26%)
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	34/55 (62%)