Protein Alignment MEOX1 and Dbx

DIOPT Version :10

• Sequence 1: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 349
• Identity: 82/349 - (23%)
• Similarity: 105/349 - (30%)
• Gaps: 147/349 - (42%)

Human    24 NPHSEGN-----GASGLPHYPPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSLPQEEHIFTE 83
            :|||..:     || |..|:|...|..||.|                     ||...|::....:
  Fly   223 HPHSHHHHHHHPGA-GHAHFPHPAFLTHQLP---------------------PHQHHQQQQHVQQ 265

Human    84 QHP---AFPQ------SPNWHFPVSDARR-------------------RP----NSGPAGGS--- 113
            |||   ..||      ||......||...                   ||    ||.|...|
  Fly   266 QHPGNSCQPQTASSSSSPGSTISDSDNNHGASTANGNGSGTGNSGQDARPHELANSNPDEDSSAS 330

Human   114 ------KEMGTSSLGLVDTTGGPGDDYG-------------------------VLGSTANETEKK 147
                  |:.....||...|.||.|..:|                         .|..|.|.....
  Fly   331 RRLTQDKQQQQQLLGAGGTGGGGGGGHGHGHPTPPPPPPPPVIAKPMPSRPTPFLPHTLNHPHLH 395

Human   148 S----SRRRKESSDNQ--------------ENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHN 194
            |    .|....|...|              ..||||.   :....|..|:..|.:.||..|....
  Fly   396 SLLAHCRNPYMSVGAQVFPLPPGQGFPWAHSTRGKPR---RGMMRRAVFSDSQRKGLEKRFQQQK 457

Human   195 YLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVK-------GGQ------------------- 233
            |:::..|.::|..|.|.:.|||:|||||||||:..|       ||.
  Fly   458 YISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERELLASGGSRDQTLPNKNNPNPDLSDAK 522

Human   234 ------PISPNGQDPEDGDSTASP 251
                  |:||:...| :|.:|..|
  Fly   523 CDRPLTPLSPSLLSP-NGSATPPP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		33/175 (19%)
		Homeodomain	172..228	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		10/57 (18%)
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	23/53 (43%)