Protein Alignment MEOX1 and cad

DIOPT Version :10

• Sequence 1: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 360
• Identity: 82/360 - (22%)
• Similarity: 106/360 - (29%)
• Gaps: 169/360 - (46%)

Human    26 HSEGN----GASGLP--------HYPPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSL-PQE 77
            ||..|    .|:|.|        |.||.    ||   ||....:::    |:..||..|.: ...
  Fly    15 HSAANLAYASAAGQPWNWTPNYHHTPPN----HQ---FLGDVDSSH----AAHHAAAAHQMYYNS 68

Human    78 EHIFTEQHPAFPQSP-NWHFPVSD------------------------ARRRPNSGPAGGSKEMG 117
            .|:|   |.|...|. .||.|.|.                        |....:|..:|.|...|
  Fly    69 HHMF---HSAAAASAGEWHSPASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGG 130

Human   118 ----------TSSLGLVDTTGGPGDDYGVLGST-------------------------------- 140
                      .||:|:    ||.|...||.|:|
  Fly   131 APGAPQLNETNSSIGV----GGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEIS 191

Human   141 ----------------------ANETEKKSSRRRKESSDNQENRG-------------------- 163
                                  ||.....::.....|:.|..|..
  Fly   192 SPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWM 256

Human   164 -KP-----------------------EGSSKAR---KERTAFTKEQLRELEAEFAHHNYLTRLRR 201
             ||                       :.|.|.|   |.|..:|..|..|||.|:....|:|..|:
  Fly   257 KKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRK 321

Human   202 YEIAVNLDLSERQVKVWFQNRRMKWKR--VKGGQP 234
            .|:|..|.|||||||:||||||.|.::  .||..|
  Fly   322 SELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDP 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		33/227 (15%)
		Homeodomain	172..228	CDD:459649	29/58 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		3/10 (30%)
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	28/54 (52%)