Protein Alignment MEOX1 and B-H2

DIOPT Version :10

• Sequence 1: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Sequence 2: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 282
• Identity: 72/282 - (25%)
• Similarity: 95/282 - (33%)
• Gaps: 98/282 - (34%)

Human    37 HYPP--TPFSFHQKPDFLATATAAYPDFSASCLAAT-----------PHSLPQE----------- 77
            |.||  .|::.|..|..|   .|.:|....:.|...           ||.|..|
  Fly   164 HSPPGNNPYAHHPMPPHL---LAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHRHG 225

Human    78 --------------EHIFTEQHPAFPQSPNWHFPVSDARRRP----------------------- 105
                          .|:..:||     .|:.|.|:.|.|.|.
  Fly   226 HGLTGDPAQHLSHLSHLSHQQH-----HPHLHHPMHDERSRSPLMLQQLGGNGGNNNNNNNNSSS 285

Human   106 ---------NSGPAGGSKEMGTSSLGLVDT--------TGGPGDDY-GVLGSTANETEKKSSRRR 152
                     ||..|..:...|.||....:.        .||||... |...||.::::......:
  Fly   286 ASNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDSDSDDCGGK 350

Human   153 KESSDNQENRGKPEG-----------SSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAV 206
            .:..|:....|....           |.|.||.|||||..||:.||..|....||:...|.|:|.
  Fly   351 DDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQDRMELAN 415

Human   207 NLDLSERQVKVWFQNRRMKWKR 228
            .|:||:.|||.|:||||.||||
  Fly   416 KLELSDCQVKTWYQNRRTKWKR 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		27/143 (19%)
		Homeodomain	172..228	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		2/2 (100%)
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	30/55 (55%)