Protein Alignment Wdr37 and YTM1

DIOPT Version :10

• Sequence 1: NP_650723.1
• Gene: Wdr37 / 42218
• FlyBaseID: FBgn0038617
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_014915.3
• Gene: YTM1 / 854446
• SGDID: S000005798
• Length: 460
• Species: Saccharomyces cerevisiae
• Alignment Length: 395
• Identity: 97/395 - (24%)
• Similarity: 167/395 - (42%)
• Gaps: 59/395 - (14%)

  Fly    98 VAGSFLAAASSTHKSLKAKLSSATGGSKAKASNKIKAQTSRIVSSFKAPTVVSTVVREFGGHKDG 162
            :.|..|  .:|.|..|..|      |..::||..::...:.:..|:         :..| .::|.
Yeast    59 IEGELL--RTSLHDYLTKK------GLSSEASLNVEYTRAILPPSY---------LNSF-SNEDW 105

  Fly   163 IWQVAAKAGQPIIGTASADHTACIWGVESARCLLQYQGHAGSVNSIKFHQQRDLVLTGSGDGTAH 227
            :..:....|...|.:.|.|.....|.: |.....||.||:|.:.::|:.....||..|: |.|..
Yeast   106 VSSLDVGDGSKHIISGSYDGIVRTWDL-SGNVQKQYSGHSGPIRAVKYISNTRLVSAGN-DRTLR 168

  Fly   228 IWQAAVNWEVPKKGHSSEEELDDSDEQVEDRDRVDTLRTPLCEFTGPGGHLSVVVAADWLSSMDQ 292
            :|:.. |.::........:|.||.:..:||...:..|.          ||.:.||:.| :|...:
Yeast   169 LWKTK-NDDLKLTSQQQAQEDDDDEVNIEDGKTLAILE----------GHKAPVVSID-VSDNSR 221

  Fly   293 IITGSWDRTAILW-----DVETGLPLQPLTGHDHELTHVSAHPTQRLVVTASRDTTFRLWDFREA 352
            |::.|:|.:...|     ::....||:.:...::::: .:|...::|.:   :|.|.|    |.|
Yeast   222 ILSASYDNSIGFWSTIYKEMTVVDPLEDINNPNNKIS-TAARKRRKLTM---KDGTIR----RRA 278

  Fly   353 IPAVSVFQGHTETVTSSVFARDDKVV--SGSDDRTIKVWELRNMRSALATIRTDSSVNRLA-VST 414
              .:|:.:.||..|...:|...|..|  |.|.|.|||.|:|...| .:.|..|..|:..:| :||
Yeast   279 --PLSLLESHTAPVEQVIFDSTDNTVGYSVSQDHTIKTWDLVTAR-CIDTRTTSYSLLSIAQLST 340

  Fly   415 GGIIAIPHDNRQIRLFDLNGQRVARLPRTSRQ---GHRRMVSSVAWAEEPLLDCDLFSCGFDRRV 476
            ..::|.....|.|.|.|   .||....:.::|   ||:..|||:....|.  :..|.|...|..|
Yeast   341 LNLLACGSSARHITLHD---PRVGASSKVTQQQLIGHKNFVSSLDTCPEN--EYILCSGSHDGTV 400

  Fly   477 FGWSI 481
            ..|.:
Yeast   401 KVWDV 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr37	NP_650723.1	WD40	153..476	CDD:238121	85/333 (26%)
		WD40 repeat	164..200	CDD:293791	8/35 (23%)
		WD40 repeat	205..274	CDD:293791	14/68 (21%)
		WD40 repeat	282..317	CDD:293791	9/39 (23%)
		WD40 repeat	323..360	CDD:293791	8/36 (22%)
		WD40 repeat	366..403	CDD:293791	14/38 (37%)
		WD40 repeat	407..430	CDD:293791	6/23 (26%)
		WD40 repeat	452..481	CDD:293791	9/28 (32%)
YTM1	NP_014915.3	NLE	8..72	CDD:462380	4/14 (29%)
		WD40	103..451	CDD:238121	86/333 (26%)
		WD40 repeat	106..142	CDD:293791	8/36 (22%)
		WD40 repeat	148..206	CDD:293791	14/69 (20%)
		WD40 repeat	242..284	CDD:293791	10/51 (20%)
		WD40 repeat	290..326	CDD:293791	13/36 (36%)
		WD40 repeat	332..372	CDD:293791	11/42 (26%)
		WD40 repeat	378..403	CDD:293791	8/26 (31%)