Protein Alignment Wdr37 and wdr37

DIOPT Version :9

• Sequence 1: NP_650723.1
• Gene: Wdr37 / 42218
• FlyBaseID: FBgn0038617
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: XP_012819659.1
• Gene: wdr37 / 100125083
• XenbaseID: XB-GENE-5740160
• Length: 495
• Species: Xenopus tropicalis
• Alignment Length: 475
• Identity: 239/475 - (50%)
• Similarity: 303/475 - (63%)
• Gaps: 58/475 - (12%)

  Fly    28 RARLHVLFAQIEREFEQLYLENQALQEKLDIATTTKESLIPPDARSAAGGSMSTQASSAALATPA 92
            |..|..||.|||||||.|||||..|:.::|
 Frog    55 RNTLLELFGQIEREFENLYLENLELRREID----------------------------------- 84

  Fly    93 TQTDEVA--GSFLAAASSTHKSLKAKLSSATGGSKAKASNKIKAQTSRIVSSFKAPT--VVSTVV 153
            |..|.:|  |..:..|..:...:|.|.|.:|.....|.....||.||:||||||..|  .:..:|
 Frog    85 TLNDRLAVEGQAIDGAELSKGQMKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLV 149

  Fly   154 REFGGHKDGIWQVAAKAGQPII-GTASADHTACIWGVESARCLLQYQGHAGSVNSIKFHQQRDLV 217
            :::.||:||:|.|:....||:: |||||||||.:|.:|:.:||::|.||||||||||||....:.
 Frog   150 KDYVGHRDGLWDVSVTRTQPVVLGTASADHTALLWSIETGKCLIKYVGHAGSVNSIKFHPTEQIA 214

  Fly   218 LTGSGDGTAHIWQAAVNWEVPK-----KGHSSEEELDDSDEQVEDRD-----RVDTLRTPLCEFT 272
            ||.|||.|||||:..|....|:     ...|.|||:|.||:...|.|     ...|:|.||   |
 Frog   215 LTASGDQTAHIWRYMVQLPTPQPTADTSQISGEEEVDFSDKDENDGDGDASSDCPTVRVPL---T 276

  Fly   273 GPGGHLSVVVAADWLSSMDQIITGSWDRTAILWDVETGLPLQPLTGHDHELTHVSAHPTQRLVVT 337
            ....|..||:|||||....|.:|.||||||.|:||||...:..|||||.||||...|||||||||
 Frog   277 ALKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVT 341

  Fly   338 ASRDTTFRLWDFRE-AIPAVSVFQGHTETVTSSVFARDDKVVSGSDDRTIKVWELRNMRSALATI 401
            :||||||||||||: :|.:|:||||||:||||:||...|.|||||||||:|||:|:||||.:|||
 Frog   342 SSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATI 406

  Fly   402 RTDSSVNRLAVSTG-GIIAIPHDNRQIRLFDLNGQRVARLPRTSRQGHRRMVSSVAWAEE-PLLD 464
            ||||::||::||.| .|||:||||||:||||::|.|:|||||::||||||||...||:|: |  .
 Frog   407 RTDSAINRISVSVGQRIIALPHDNRQVRLFDMSGVRLARLPRSNRQGHRRMVCCCAWSEDHP--T 469

  Fly   465 CDLFSCGFDRRVFGWSIVLP 484
            |:||:|||||:..||:|.:|
 Frog   470 CNLFTCGFDRQAIGWNINIP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wdr37	NP_650723.1	WD40	153..476	CDD:238121	196/336 (58%)
		WD40 repeat	164..200	CDD:293791	18/36 (50%)
		WD40	198..>481	CDD:225201	176/295 (60%)
		WD40 repeat	205..274	CDD:293791	33/78 (42%)
		WD40 repeat	282..317	CDD:293791	18/34 (53%)
		WD40 repeat	323..360	CDD:293791	27/37 (73%)
		WD40 repeat	366..403	CDD:293791	26/36 (72%)
		WD40 repeat	407..430	CDD:293791	15/23 (65%)
		WD40 repeat	452..481	CDD:293791	15/29 (52%)
wdr37	XP_012819659.1	WD40	128..437	CDD:238121	177/311 (57%)
		WD40 repeat	203..280	CDD:293791	32/79 (41%)
		WD40 repeat	285..321	CDD:293791	19/35 (54%)
		WD40 repeat	328..365	CDD:293791	26/36 (72%)
		WD40 repeat	371..406	CDD:293791	24/34 (71%)
		WD40 repeat	412..452	CDD:293791	25/39 (64%)
		WD40 repeat	459..484	CDD:293791	12/26 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5244
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40914
Inparanoid	1	1.050	431	1.000	Inparanoid score	I1683
OMA	1	1.010	-	-		QHG52450
OrthoDB	1	1.010	-	-		D1338925at2759
OrthoFinder	1	1.000	-	-		FOG0004215
OrthoInspector	1	1.000	-	-		otm49407
Panther	1	1.100	-	-	LDO	PTHR19855
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4175
SonicParanoid	1	1.000	-	-		X4028
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110