Protein Alignment Vha100-2 and Vha100-1

DIOPT Version :10

• Sequence 1: NP_650722.1
• Gene: Vha100-2 / 42216
• FlyBaseID: FBgn0028670
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: NP_651672.1
• Gene: Vha100-1 / 43442
• FlyBaseID: FBgn0028671
• Length: 855
• Species: Drosophila melanogaster
• Alignment Length: 861
• Identity: 503/861 - (58%)
• Similarity: 615/861 - (71%)
• Gaps: 46/861 - (5%)

  Fly     1 MGDMFRSEEMALCQMFIQPEAAYTSVSELGETGCVQFRDLNVNVNAFQRKFVTEVRRCDELERKI 65
            ||.:||||||||||:|:|.||||..||||||.|.|||||||.:|||||||||.|||||||:|||:
  Fly     1 MGSLFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKL 65

  Fly    66 RYIETEIKKDGIVLPDIQDDIPRAPNPREIIDLEAHLEKTESEMIELAQNEVNMKSNYLELTELR 130
            ||:|.|||||||.:.|..:. |.||.|||:|||||..||.|:|:.|:.||...:|.|:||||||:
  Fly    66 RYLEKEIKKDGIPMLDTGES-PEAPQPREMIDLEATFEKLENELREVNQNAEALKRNFLELTELK 129

  Fly   131 KVLENTQGFFSDQEVLNLDSSNRA-----------GGDN---DAAAQHRG-------------RL 168
            .:|..||.|| |:.|..:..|:.|           ..||   |..||..|             :|
  Fly   130 HILRKTQVFF-DESVPTVYKSSGAYSSSKYRRYPQMADNQNEDEQAQLLGEEGVRASQPGQNLKL 193

  Fly   169 GFVAGVINRERVFAFERMLWRISRGNVFLKRSDLDEPLNDPATGHPIYKTVFVAFFQGEQLKNRI 233
            |||||||.|||:.||||||||..||||||:::.::.||.||..|..::|:||:.||||:|||.|:
  Fly   194 GFVAGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTNGDQVHKSVFIIFFQGDQLKTRV 258

  Fly   234 KKVCTGFHASLYPCPSSHNEREEMVRNVRTRLEDLKLVLSQTEDHRSRVLATVSKNLPSWSIMVK 298
            ||:|.||.|:|||||.:..:|.||...|.||:|||..||.||:|||.|||...:|||.:|.:.|:
  Fly   259 KKICEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQDHRHRVLVAAAKNLKNWFVKVR 323

  Fly   299 KMKAIYHTLNLFNMDVTKKCLIGECWVPTNDLPVVQKALSDGSAAVGSTIPSFLNVIDTNEQPPT 363
            |:|||||||||||:|||:||||.|||||..|:..:|.||..|:...||::|..||.:.|.|.|||
  Fly   324 KIKAIYHTLNLFNLDVTQKCLIAECWVPLLDIETIQLALRRGTERSGSSVPPILNRMQTFENPPT 388

  Fly   364 FNRTNKFTRGFQNLIDAYGVASYRECNPALYTCITFPFLFAVMFGDLGHGLILVLFGAWMVLCER 428
            :|||||||:.||.||||||||||||.|||.||.|||||||||||||||||.|:.|||.||:..|:
  Fly   389 YNRTNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRKEK 453

  Fly   429 KLARIRNGGEIWNIFFGGRYIILLMGLFAMYTGLVYNDVFSKSMNLFGSRWFNNYNTTTVLTNPN 493
            .||..:...|||||||||||||.|||:|:|||||:|||:||||:|:|||.|..:||.:||:.|..
  Fly   454 GLAAQKTDNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLSYNKSTVMENKF 518

  Fly   494 LQLPPNSSAVGV-YPFGMDPVWQLAD-NKIIFLNSFKMKLSIIFGVLHMVFGVCMSVVNFTHFKR 556
            |||.|.....|. |||||||:||:|. |||||.|::|||:||||||:||:|||.||..|.|:|:.
  Fly   519 LQLSPKGDYEGAPYPFGMDPIWQVAGANKIIFHNAYKMKISIIFGVIHMIFGVVMSWHNHTYFRN 583

  Fly   557 YASIFLEFVPQILFLLLLFGYMVFMMFFKWFSYNARTSFQPETPGCAPSVLIMFINMMLFKNTE- 620
            ..|:..||:||::||||||.|||.:||.||..: |.|:.:|.:..||||:||.||:|:||...:
  Fly   584 RISLLYEFIPQLVFLLLLFFYMVLLMFIKWIKF-AATNDKPYSEACAPSILITFIDMVLFNTPKP 647

  Fly   621 PPKGCNEFMFESQPQLQKAFVLIALCCIPWMLLGKPLYIKFTRKNKAHANHNGQLTGNIELAEGE 685
            ||:.|..:||..|..:|..|||:|:.|||.|||.|||.|...||.           .|::...|.
  Fly   648 PPENCETYMFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIMQARKQ-----------ANVQPIAGA 701

  Fly   686 T-PLPTGFSGNEENAGGAHGH-DDEPMSEIYIHQAIHTIEYVLSTISHTASYLRLWALSLAHAQL 748
            | ....|...|..:.||..|| ::|.:|||:|||:||||||||.::|||||||||||||||||||
  Fly   702 TSDAEAGGVSNSGSHGGGGGHEEEEELSEIFIHQSIHTIEYVLGSVSHTASYLRLWALSLAHAQL 766

  Fly   749 SEVLWQMVLSLGLKMSGVGGAIGLFIIFGAWCLFTLAILVLMEGLSAFLHTLRLHWVEFMSKFYE 813
            :||||.||||:|||..|..|.|.|..:|..|.:.|:.||||||||||||||||||||||.||||:
  Fly   767 AEVLWTMVLSIGLKQEGPVGGIVLTCVFAFWAILTVGILVLMEGLSAFLHTLRLHWVEFQSKFYK 831

  Fly   814 GMGYAFQPFSFKAILD 829
            |.|||||||||.||::
  Fly   832 GQGYAFQPFSFDAIIE 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-2	NP_650722.1	V_ATPase_I	27..824	CDD:460232	480/828 (58%)
Vha100-1	NP_651672.1	V_ATPase_I	27..842	CDD:460232	480/828 (58%)