Protein Alignment Vha100-2 and LOC3290488

DIOPT Version :10

• Sequence 1: NP_650722.1
• Gene: Vha100-2 / 42216
• FlyBaseID: FBgn0028670
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: XP_321521.3
• Gene: LOC3290488 / 3290488
• VectorBaseID: AGAMI1_011388
• Length: 831
• Species: Anopheles gambiae
• Alignment Length: 848
• Identity: 609/848 - (71%)
• Similarity: 701/848 - (82%)
• Gaps: 34/848 - (4%)

  Fly     1 MGDMFRSEEMALCQMFIQPEAAYTSVSELGETGCVQFRDLNVNVNAFQRKFVTEVRRCDELERKI 65
            |..||||||||||||||||||||||||||||||.|||||||.:|||||||||:|||||||:|||:
Mosquito     1 MAMMFRSEEMALCQMFIQPEAAYTSVSELGETGAVQFRDLNADVNAFQRKFVSEVRRCDEMERKL 65

  Fly    66 RYIETEIKKDGIVLPDIQ-DDIPRAPNPREIIDLEAHLEKTESEMIELAQNEVNMKSNYLELTEL 129
            ||:|.|:|||.:.:|:.. ||.||||||||||||||.|||||:|::||:||.||:||||||||||
Mosquito    66 RYVEGEVKKDSVQIPECSVDDWPRAPNPREIIDLEARLEKTENEILELSQNAVNLKSNYLELTEL 130

  Fly   130 RKVLENTQGFFSDQEVLNLDSSNRAG--GDNDAAAQHRGRLGFVAGVINRERVFAFERMLWRISR 192
            :.|||.||.||.:|||:....:.::.  .::..|||.|||||||||||.||::..||||||||||
Mosquito   131 KHVLERTQSFFFEQEVIVSTDAAKSNLIAEDPTAAQSRGRLGFVAGVIQREKMPGFERMLWRISR 195

  Fly   193 GNVFLKRSDLDEPLNDPATGHPIYKTVFVAFFQGEQLKNRIKKVCTGFHASLYPCPSSHNEREEM 257
            ||:||::.:|:|||.|||||:.|:||||||||||||||.||||||||:|.||||||||.:||.:|
Mosquito   196 GNIFLRQVELEEPLEDPATGNEIFKTVFVAFFQGEQLKARIKKVCTGYHVSLYPCPSSGSERTDM 260

  Fly   258 VRNVRTRLEDLKLVLSQTEDHRSRVLATVSKNLPSWSIMVKKMKAIYHTLNLFNMDVTKKCLIGE 322
            |:.|.||||||::||:||:|||:.|||:|:|.|.||.||||||||||||||||||||||||||||
Mosquito   261 VKGVCTRLEDLRMVLNQTQDHRAIVLASVAKELFSWRIMVKKMKAIYHTLNLFNMDVTKKCLIGE 325

  Fly   323 CWVPTNDLPVVQKALSDGSAAVGSTIPSFLNVIDTNEQPPTFNRTNKFTRGFQNLIDAYGVASYR 387
            ||||..|||.|||||||||||||||||||||||||||.|||:||||||||||||||||||:||||
Mosquito   326 CWVPVPDLPKVQKALSDGSAAVGSTIPSFLNVIDTNEAPPTYNRTNKFTRGFQNLIDAYGIASYR 390

  Fly   388 ECNPALYTCITFPFLFAVMFGDLGHGLILVLFGAWMVLCERKLARIRNGGEIWNIFFGGRYIILL 452
            |.||||||.|||||||.:||||||||:|:.|||.|||..|:||...::..|||||||||||||||
Mosquito   391 EANPALYTIITFPFLFGIMFGDLGHGMIMALFGLWMVTGEKKLGAKKSTNEIWNIFFGGRYIILL 455

  Fly   453 MGLFAMYTGLVYNDVFSKSMNLFGSRWFNNYNTTTVLTNPNLQLPPNSS--AVGVYPFGMDPVWQ 515
            ||||:||||.||||:||||||:|||.|..||||:||:||.:|.|.|.|:  ...:||.|:|||||
Mosquito   456 MGLFSMYTGFVYNDIFSKSMNIFGSAWSINYNTSTVMTNKDLTLNPGSTDYDTEIYPIGLDPVWQ 520

  Fly   516 LADNKIIFLNSFKMKLSIIFGVLHMVFGVCMSVVNFTHFKRYASIFLEFVPQILFLLLLFGYMVF 580
            ||.||||||||:||||||||||:||:|||||||||...||:..||.|||:|||:||:|||.||||
Mosquito   521 LASNKIIFLNSYKMKLSIIFGVVHMIFGVCMSVVNHNFFKKRISIVLEFLPQIIFLVLLFAYMVF 585

  Fly   581 MMFFKWFSYNARTSFQPETPGCAPSVLIMFINMMLFKNTEPPKGCNEFMFESQPQLQKAFVLIAL 645
            |||.||.:|.|:|.:||.||||||||||||||||||||:||..||:|||||.|.:||:.||.|||
Mosquito   586 MMFMKWIAYTAKTDYQPRTPGCAPSVLIMFINMMLFKNSEPFHGCDEFMFEGQNELQRTFVFIAL 650

  Fly   646 CCIPWMLLGKPLYIKFTRKNKAHANHNGQLTGNIELAEGETPLPTGFSGNEENAGGAH------- 703
            .||||||||||.|:.|.|||.:                 .||:|.  :|:....|.|:
Mosquito   651 LCIPWMLLGKPFYLMFKRKNAS-----------------PTPIPN--NGDVHQGGDANHTSSSPK 696

  Fly   704 ---GHDDEPMSEIYIHQAIHTIEYVLSTISHTASYLRLWALSLAHAQLSEVLWQMVLSLGLKMSG 765
               .||||||:||:||||||||||||||:||||||||||||||||||||||||.||||:|||.:.
Mosquito   697 PHDSHDDEPMAEIFIHQAIHTIEYVLSTVSHTASYLRLWALSLAHAQLSEVLWNMVLSMGLKQTS 761

  Fly   766 VGGAIGLFIIFGAWCLFTLAILVLMEGLSAFLHTLRLHWVEFMSKFYEGMGYAFQPFSFKAILDG 830
            ..|||.|:.:||||.||||||||:|||||||||||||||||||||||||:||.|||||||.|:|.
Mosquito   762 YKGAIMLYFVFGAWSLFTLAILVMMEGLSAFLHTLRLHWVEFMSKFYEGLGYGFQPFSFKLIIDS 826

  Fly   831 EEE 833
            :::
Mosquito   827 DDD 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-2	NP_650722.1	V_ATPase_I	27..824	CDD:460232	580/811 (72%)
LOC3290488	XP_321521.3	None