Protein Alignment Vha100-4 and tcirg1

DIOPT Version :10

• Sequence 1: NP_650720.1
• Gene: Vha100-4 / 42214
• FlyBaseID: FBgn0038613
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_012809053.3
• Gene: tcirg1 / 549603
• XenbaseID: XB-GENE-5721917
• Length: 865
• Species: Xenopus tropicalis
• Alignment Length: 840
• Identity: 350/840 - (41%)
• Similarity: 511/840 - (60%)
• Gaps: 41/840 - (4%)

  Fly    15 SIFRSEVMSLVQMYLQPEAAYDTIAALGEVGCVQFRDLNAKINAQQRKFIGEVRRCDELERRIRY 79
            |:||.|.|.|.|::||..:.|..::||||:|.|:|||||..:|:.||:::.|:|||||:|....|
 Frog    45 SLFRGEEMCLAQLFLQSGSEYQCVSALGELGLVEFRDLNQNVNSFQRRYVSEIRRCDEMETTFSY 109

  Fly    80 VTAELNKEGHKVLDLMDDFPPAPQPREIIDLELHLEKTETEILELAANNVNLQTSYLELSEMIQV 144
            :..||.|.|.:|.: .:..||||.||:.|.::...|:...|:.|::.|...||....||.|...:
 Frog   110 LERELRKAGVQVPE-SEMSPPAPLPRDAIRMQEESEQLAKELREVSQNRQTLQERLRELLEYANI 173

  Fly   145 LERTDQF---FSDQESHNFDLNKMGTHRDP---EKSNGHLGFVAGVISREREYAFERMLWRISRG 203
            |..:.:|   ..:.|:...|.::.....||   .|.:..:.|:||||...|..:|||:|||..||
 Frog   174 LRESQRFTGPLLESEAQWKDRSEDDPLLDPAVVNKQDLRVSFMAGVIHPWRMNSFERLLWRACRG 238

  Fly   204 NVFVRRCDVDVALTDPKTGNVLHKSVFVVFFQGDQLQARIRKVCTGFHAHMYPCPSSHSERQEMV 268
            .:.|...::...:.|..||..:.:.:|::.:.|:::..:|:|:...||.|:||.....:.|.|.:
 Frog   239 YLIVNFVEMSEPMEDLVTGESVTQIIFLISYWGEKIGEKIKKIANCFHCHIYPYADDETSRLETL 303

  Fly   269 KNVRTRLEDLQVIINQTSDHRTCVLQAALKQLPTWSAMVKKMKGIYHTLNLFNVDLGSKCLIGEG 333
            :|:..:::|:|.::.||..:.:.||..|...|..|...|:|||.||..|||.:|  ..:|||||.
 Frog   304 RNLLVQIQDMQKVLLQTEGYLSQVLSRAASALHHWRVSVRKMKHIYLILNLCSV--RERCLIGEV 366

  Fly   334 WVPKRELELVEVALAAGSASVGSTVPSFINVLDTKKEPPTHFRTNKFTRGFQNLIDAYGIAGYRE 398
            |.|..:|.|::.||...|.|.|....||.:.:.....|||..||||||.|||.::||||:|.|:|
 Frog   367 WCPVVDLPLLQSALTRASESSGGGGESFCHRIPCAFSPPTLIRTNKFTSGFQGIVDAYGVATYQE 431

  Fly   399 VNPGLYTCITFPFLFAVMFGDMGHGTILFLLGLWMVIDEKRLSKKRG-GEIWNIFFAGRYIIMLM 462
            |||.:::.|||||||||||||:|||.|:||..||:|:.|.....:|. .||:::.|.|||:|:||
 Frog   432 VNPAIFSIITFPFLFAVMFGDVGHGAIMFLFALWLVLGENDPKLRRSEDEIFSMCFGGRYLILLM 496

  Fly   463 GLFAMYTGFHYNDIFSKSINVFGTRW-------VNVYNRTTVLTNPTLQLNPSVATRGV----YP 516
            |..::||||.||:.||:...:|.:.|       .|.:...::...|.:.|||::.  ||    ||
 Frog   497 GALSVYTGFVYNECFSRPAVIFNSGWSVASMARANNWTSDSINKLPPIPLNPNIT--GVFTAPYP 559

  Fly   517 MGIDPIWQSASNKIIFLNTYKMKLSIIFGVLHMVFGVCMSVENFVFFKKYAYIILQFVPQVLFLL 581
            .||||||..|.|::.|||::|||:|:|.||.||.||||:||.|||.|::...|.|..:|::||||
 Frog   560 FGIDPIWSLAVNRLTFLNSFKMKMSVILGVCHMAFGVCLSVFNFVHFRQIYRIFLITLPELLFLL 624

  Fly   582 LMFGYMCFMMFYKWVKYSPTTDVEADTPGCAPSVLIMFIDMVLFKTETALPGCDVNMFPIQKNLE 646
            .:|||:.||:.|||:.      :.|:....|||:||.||||.||   |..|| :.:::..|:.::
 Frog   625 CLFGYLVFMVVYKWIV------LTAEDAEWAPSILIHFIDMFLF---TQNPG-NRDLYQGQQVVQ 679

  Fly   647 MIFLVVALLCIPWILLGKPLYIKYQRRNRPAGPVEEVDEIVEKIEVTTG-KEIIITEVAEAHESG 710
            .:.::||:||||.:|||.|:.:..|.|::.....:      .:..:..| :|.::.:........
 Frog   680 TVLVIVAILCIPVLLLGDPICLLIQHRSKKDSSHQ------NRCSLNNGDREALLEDEITVPTGH 738

  Fly   711 GHSEEDDEPMSEIWIHQAIHTIEYILSTISHTASYLRLWALSLAHAQLSEVLWTMVLAMGLQMNG 775
            ||..|..: .:|:::||.||||||.|..||:||||||||||||||||||||||.||:.:|.....
 Frog   739 GHGSEKFD-TAEVFMHQMIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWNMVIRIGFSKLS 802

  Fly   776 YVGAIGLFFIFAVWEFFTIAIMVMMEGLSAFLHTLRLHWVEFMSKFYVGNGYPFTPFSFK 835
            ....|.|..|||.:...|:||:::|||||||||.||||||||.:|||.|.||.|.||.|:
 Frog   803 LTWGIVLVPIFAFFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGEGYKFFPFCFE 862

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-4	NP_650720.1	V_ATPase_I	39..834	CDD:460232	339/813 (42%)
tcirg1	XP_012809053.3	V_ATPase_I	69..861	CDD:460232	339/813 (42%)